1WAQ
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
Summary for 1WAQ
Entry DOI | 10.2210/pdb1waq/pdb |
Related | 2BHK |
Descriptor | GROWTH/DIFFERENTIATION FACTOR 5, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | growth factor, tgf-beta superfamily, cytokine |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P43026 |
Total number of polymer chains | 1 |
Total formula weight | 13760.00 |
Authors | Mueller, T.D.,Nickel, J.,Sebald, W. (deposition date: 2004-10-27, release date: 2005-05-19, Last modification date: 2023-12-13) |
Primary citation | Nickel, J.,Kotzsch, A.,Sebald, W.,Mueller, T.D. A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib. J.Mol.Biol., 349:933-, 2005 Cited by PubMed: 15890363DOI: 10.1016/J.JMB.2005.04.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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