2B0U
The Structure of the Follistatin:Activin Complex
Summary for 2B0U
Entry DOI | 10.2210/pdb2b0u/pdb |
Descriptor | Inhibin beta A chain, Follistatin, IRIDIUM (III) ION, ... (6 entities in total) |
Functional Keywords | activin, follistatin, tgf-beta, morphogen, inhibin, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P08476 P19883 |
Total number of polymer chains | 4 |
Total formula weight | 90655.58 |
Authors | Thompson, T.B.,Lerch, T.F.,Cook, R.W.,Woodruff, T.K.,Jardetzky, T.S. (deposition date: 2005-09-14, release date: 2005-10-11, Last modification date: 2017-10-11) |
Primary citation | Thompson, T.B.,Lerch, T.F.,Cook, R.W.,Woodruff, T.K.,Jardetzky, T.S. The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding. Dev.Cell, 9:535-543, 2005 Cited by PubMed: 16198295DOI: 10.1016/j.devcel.2005.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report