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PDB: 86 results

1TFG
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AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
Descriptor: TRANSFORMING GROWTH FACTOR, BETA 2
Authors:Gruetter, M, Schlunegger, M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
2DGK
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BU of 2dgk by Molmil
Crystal structure of an N-terminal deletion mutant of Escherichia coli GadB in an autoinhibited state (aldamine)
Descriptor: 1,2-ETHANEDIOL, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGL
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BU of 2dgl by Molmil
Crystal structure of Escherichia coli GadB in complex with bromide
Descriptor: ACETIC ACID, BROMIDE ION, Glutamate decarboxylase beta, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGM
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Crystal structure of Escherichia coli GadB in complex with iodide
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
1RNE
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BU of 1rne by Molmil
THE CRYSTAL STRUCTURE OF RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RENIN, [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE
Authors:Gruetter, M.G, Rahuel, J, Priestle, J.P.
Deposit date:1991-12-12
Release date:1993-10-31
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.
J.Struct.Biol., 107, 1991
1SBN
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BU of 1sbn by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1991-12-20
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1SIB
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BU of 1sib by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1993-08-02
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
2WL1
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BU of 2wl1 by Molmil
Pyrin PrySpry domain
Descriptor: 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION
Authors:Weinert, C, Mittl, P.R, Gruetter, M.G.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
1AIE
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BU of 1aie by Molmil
P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE
Descriptor: P53
Authors:Mittl, P.R.E, Chene, P, Gruetter, M.G.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template.
Acta Crystallogr.,Sect.D, 54, 1998
2V50
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BU of 2v50 by Molmil
The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug Exporter MexB
Descriptor: DODECYL-BETA-D-MALTOSIDE, MULTIDRUG RESISTANCE PROTEIN MEXB
Authors:Sennhauser, G, Bukowska, M.A, Gruetter, M.G.
Deposit date:2008-10-01
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa.
J.Mol.Biol., 389, 2009
1BX7
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BU of 1bx7 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1BX8
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BU of 1bx8 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
2FBE
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BU of 2fbe by Molmil
Crystal Structure of the PRYSPRY-domain
Descriptor: PREDICTED: similar to ret finger protein-like 1
Authors:Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G.
Deposit date:2005-12-09
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
1C94
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BU of 1c94 by Molmil
REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD.
Descriptor: RETRO-GCN4 LEUCINE ZIPPER
Authors:Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G.
Deposit date:1999-07-30
Release date:2000-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure.
Proc.Natl.Acad.Sci.USA, 97, 2000
3EO0
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BU of 3eo0 by Molmil
Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, GLYCEROL
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
5FIO
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BU of 5fio by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
5FIN
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BU of 5fin by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
2I1B
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BU of 2i1b by Molmil
CRYSTALLOGRAPHIC REFINEMENT OF INTERLEUKIN-1 BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-1 BETA
Authors:Priestle, J.P, Schaer, H.-P, Gruetter, M.G.
Deposit date:1990-01-02
Release date:1990-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.
Proc.Natl.Acad.Sci.USA, 86, 1989
3EO1
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BU of 3eo1 by Molmil
Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, Transforming growth factor beta-3
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
4HJ0
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BU of 4hj0 by Molmil
Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
Descriptor: Gastric inhibitory polypeptide receptor, Gipg013 Fab, Antagonizing antibody to the GIP Receptor, ...
Authors:Madhurantakam, C, Ravn, P, Gruetter, M.G, Jackson, R.H.
Deposit date:2012-10-12
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor.
J.Biol.Chem., 288, 2013
1SVX
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BU of 1svx by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein
Descriptor: Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
154L
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BU of 154l by Molmil
THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GOOSE LYSOZYME
Authors:Weaver, L.H, Gruetter, M.G, Matthews, B.W.
Deposit date:1994-05-05
Release date:1995-01-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.
J.Mol.Biol., 245, 1995
153L
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BU of 153l by Molmil
THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE
Descriptor: GOOSE LYSOZYME
Authors:Weaver, L.H, Gruetter, M.G, Matthews, B.W.
Deposit date:1994-05-05
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.
J.Mol.Biol., 245, 1995
2RKO
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BU of 2rko by Molmil
Crystal Structure of the Vps4p-dimer
Descriptor: Vacuolar protein sorting-associated protein 4
Authors:Hartmann, C, Gruetter, M.G.
Deposit date:2007-10-17
Release date:2008-02-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p
J.Mol.Biol., 377, 2008
2V7N
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Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4
Descriptor: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN
Authors:Frey, D, Huber, T, Plueckthun, A, Gruetter, M.G.
Deposit date:2007-07-31
Release date:2008-06-17
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008

 

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