2WL1

Pyrin PrySpry domain

Summary for 2WL1

• Entry DOI: 10.2210/pdb2wl1/pdb
• Descriptor: PYRIN, THIOCYANATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: amyloidosis, polymorphism, cytoskeleton, actin-binding inflammatory response, metal-binding, signaling protein, disease mutation, pryspry
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 21366.45

Authors

Weinert, C.,Mittl, P.R.,Gruetter, M.G. (deposition date: 2009-06-19, release date: 2009-10-20, Last modification date: 2023-12-13)

• Primary citation: Weinert, C.,Gruetter, C.,Roschitzki-Voser, H.,Mittl, P.R.,Gruetter, M.G.; The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.; J.Mol.Biol., 394:226-, 2009; PubMed: 19729025; DOI: 10.1016/J.JMB.2009.08.059

Experimental method

X-RAY DIFFRACTION (1.35 Å)