2V50

The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug Exporter MexB

Summary for 2V50

DescriptorMULTIDRUG RESISTANCE PROTEIN MEXB, DODECYL-BETA-D-MALTOSIDE (2 entities in total)
Functional Keywordsmultidrug resistance protein, ddm, rnd, membrane, detergent, transport, cell membrane, transmembrane, membrane protein, cell inner membrane, antibiotic resistance, drug-efflux pump, transport protein
Biological sourcePSEUDOMONAS AERUGINOSA PA01
Cellular locationCell inner membrane; Multi-pass membrane protein P52002
Total number of polymer chains6
Total molecular weight686320.97
Authors
Sennhauser, G.,Bukowska, M.A.,Gruetter, M.G. (deposition date: 2008-10-01, release date: 2009-05-19, Last modification date: 2018-01-24)
Primary citation
Sennhauser, G.,Bukowska, M.A.,Briand, C.,Gruetter, M.G.
Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa.
J.Mol.Biol., 389:134-, 2009
PubMed: 19361527 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2009.04.001
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.284352.8%12.6%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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