3EO0
Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Summary for 3EO0
| Entry DOI | 10.2210/pdb3eo0/pdb |
| Related | 3EO1 |
| Descriptor | GC-1008 Fab Light Chain, GC-1008 Fab Heavy Chain, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | cytokine neutralizing antibody, fab fragment, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 4 |
| Total formula weight | 95102.06 |
| Authors | Gruetter, C.,Gruetter, M.G. (deposition date: 2008-09-26, release date: 2008-12-02, Last modification date: 2023-11-01) |
| Primary citation | Wilkinson, T.,Turner, R.,Podichetty, S.,Finch, D.,McCourt, M.,Loning, S.,Jermutus, L. A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions Proc.Natl.Acad.Sci.Usa, 105:20251-20256, 2008 Cited by PubMed: 19073914DOI: 10.1073/pnas.0807200106 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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