1AGQ
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GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT
Descriptor:GLIAL CELL-DERIVED NEUROTROPHIC FACTOR
Authors:Eigenbrot, C., Gerber, N.
Deposit date:1997-03-25
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding.
Nat.Struct.Biol., 4, 1997
1BMP
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BONE MORPHOGENETIC PROTEIN-7
Descriptor:BONE MORPHOGENETIC PROTEIN-7
Authors:Griffith, D.L., Scott, D.L.
Deposit date:1995-12-14
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily.
Proc.Natl.Acad.Sci.USA, 93, 1996
1KLA
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES
Descriptor:TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P., Archer, S.J., Qian, S.W., Roberts, A.B., Sporn, M.B., Weatherbee, J.A., Tsang, M.L.-S., Lucas, R., Zhang, B.-L., Wenker, J., Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLC
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SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P., Archer, S.J., Qian, S.W., Roberts, A.B., Sporn, M.B., Weatherbee, J.A., Tsang, M.L.-S., Lucas, R., Zhang, B.-L., Wenker, J., Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLD
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES
Descriptor:TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P., Archer, S.J., Qian, S.W., Roberts, A.B., Sporn, M.B., Weatherbee, J.A., Tsang, M.L.-S., Lucas, R., Zhang, B.-L., Wenker, J., Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1LX5
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CRYSTAL STRUCTURE OF THE BMP7/ACTRII EXTRACELLULAR DOMAIN COMPLEX
Descriptor:bone morphogenetic protein 7, Activin Type II Receptor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Greenwald, J., Groppe, J., Kwiatkowski, W., Choe, S.
Deposit date:2002-06-04
Release date:2003-04-01
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
Mol.Cell, 11, 2003
1LXI
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REFINEMENT OF BMP7 CRYSTAL STRUCTURE
Descriptor:BONE MORPHOGENETIC PROTEIN 7, N-ACETYL-D-GLUCOSAMINE
Authors:Greenwald, J., Groppe, J., Kwiatkowski, W., Choe, S.
Deposit date:2002-06-05
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
Mol.Cell, 11, 2003
1M4U
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CRYSTAL STRUCTURE OF BONE MORPHOGENETIC PROTEIN-7 (BMP-7) IN COMPLEX WITH THE SECRETED ANTAGONIST NOGGIN
Descriptor:Bone Morphogenetic Protein-7, Noggin, N-ACETYL-D-GLUCOSAMINE
Authors:Groppe, J., Greenwald, J., Wiater, E., Rodriguez-Leon, J., Economides, A.N., Kwiatkowski, W., Affolter, M., Vale, W.W., Izpisua-Belmonte, J.C., Choe, S.
Deposit date:2002-07-03
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis of BMP Signalling Inhibition by the Cystine Knot Protein Noggin
Nature, 420, 2002
1NYS
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CRYSTAL STRUCTURE OF ACTIVIN A BOUND TO THE ECD OF ACTRIIB P41
Descriptor:activin receptor, Inhibin beta A chain
Authors:Thompson, T.B., Woodruff, T.K., Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1NYU
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CRYSTAL STRUCTURE OF ACTIVIN A BOUND TO THE ECD OF ACTRIIB
Descriptor:activin receptor, Inhibin beta A chain
Authors:Thompson, T.B., Woodruff, T.K., Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1REU
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STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN 2 MUTANT L51P
Descriptor:bone morphogenetic protein 2, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Keller, S., Nickel, J., Zhang, J.-L., Sebald, W., Mueller, T.D.
Deposit date:2003-11-07
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1S4Y
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CRYSTAL STRUCTURE OF THE ACTIVIN/ACTRIIB EXTRACELLULAR DOMAIN
Descriptor:Activin receptor type IIB precursor, Inhibin beta A chain
Authors:Greenwald, J., Vega, M.E., Allendorph, G.P., Fischer, W.H., Vale, W., Choe, S., Joint Center for Structural Genomics (JCSG)
Deposit date:2004-01-19
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-beta Family Receptors.
Mol.Cell, 15, 2004
1TFG
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AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
Descriptor:TRANSFORMING GROWTH FACTOR, BETA 2
Authors:Gruetter, M., Schlunegger, M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
1TGJ
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HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
Descriptor:TRANSFORMING GROWTH FACTOR-BETA 3, 1,4-DIETHYLENE DIOXIDE
Authors:Mittl, P.R.E., Priestle, J.P., Gruetter, M.G.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TGK
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HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
Descriptor:TRANSFORMING GROWTH FACTOR BETA 3
Authors:Mittl, P.R.E., Priestle, J.P., Gruetter, M.G.
Deposit date:1996-07-10
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1WAQ
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CRYSTAL STRUCTURE OF HUMAN GROWTH AND DIFFERENTIATION FACTOR 5 (GDF-5)
Descriptor:GROWTH/DIFFERENTIATION FACTOR 5, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Mueller, T.D., Nickel, J., Sebald, W.
Deposit date:2004-10-27
Release date:2005-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib.
J.Mol.Biol., 349, 2005
1ZKZ
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CRYSTAL STRUCTURE OF BMP9
Descriptor:Growth/differentiation factor 2
Authors:Brown, M.A., Zhao, Q., Baker, K.A., Naik, C., Chen, C., Pukac, L., Singh, M., Tsareva, T., Parice, Y., Mahoney, A., Roschke, V., Sanyal, I., Choe, S.
Deposit date:2005-05-04
Release date:2005-05-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure of BMP-9 and functional interactions with pro-region and receptors
J.Biol.Chem., 280, 2005
2ARV
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STRUCTURE OF HUMAN ACTIVIN A
Descriptor:Inhibin beta A chain, SULFATE ION, GLYCEROL, ...
Authors:Harrington, A.E., Morris-Triggs, S.A., Ruotolo, B.T., Robinson, C.V., Ohnuma, S., Hyvonen, M.
Deposit date:2005-08-22
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
2ASK
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STRUCTURE OF HUMAN ARTEMIN
Descriptor:artemin, SULFATE ION
Authors:Silvian, L., Jin, P., Carmillo, P., Boriack-Sjodin, P.A., Pelletier, C., Rushe, M., Gong, B.J., Sah, D., Pepinsky, B., Rossomando, A.
Deposit date:2005-08-23
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Artemin crystal structure reveals insights into heparan sulfate binding.
Biochemistry, 45, 2006
2BHK
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CRYSTAL STRUCTURE OF HUMAN GROWTH AND DIFFERENTIATION FACTOR 5 (GDF5)
Descriptor:GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL
Authors:Schreuder, H., Liesum, A., Pohl, J., Kruse, M., Koyama, M.
Deposit date:2005-01-12
Release date:2005-03-11
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites.
Biochem.Biophys.Res.Commun., 329, 2005
2QCQ
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CRYSTAL STRUCTURE OF BONE MORPHOGENETIC PROTEIN-3 (BMP-3)
Descriptor:Bone morphogenetic protein 3
Authors:Allendorph, G.P.
Deposit date:2007-06-19
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007
2QCW
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CRYSTAL STRUCTURE OF BONE MORPHOGENETIC PROTEIN-6 (BMP-6)
Descriptor:Bone morphogenetic protein 6
Authors:Allendorph, G.P.
Deposit date:2007-06-19
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007
2R52
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CRYSTAL STRUCTURE ANALYSIS OF BONE MORPHOGENETIC PROTEIN-6 (BMP-6)
Descriptor:Bone morphogenetic protein 6, ISOPROPYL ALCOHOL
Authors:Mueller, T.D., Sebald, W., Saremba, S.
Deposit date:2007-09-03
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2TGI
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CRYSTAL STRUCTURE OF TRANSFORMING GROWTH FACTOR-BETA2: AN UNUSUAL FOLD FOR THE SUPERFAMILY
Descriptor:TRANSFORMING GROWTH FACTOR ,BETA 2
Authors:Daopin, S., Davies, D.R.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily.
Science, 257, 1992
3BK3
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CRYSTAL STRUCTURE OF THE COMPLEX OF BMP-2 AND THE FIRST VON WILLEBRAND DOMAIN TYPE C OF CROSSVEINLESS-2
Descriptor:Bone morphogenetic protein 2, Crossveinless 2
Authors:Mueller, T.D., Sebald, W., Zhang, J.-L.
Deposit date:2007-12-05
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
Dev.Cell, 14, 2008
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