6OMN

Glycosylated BMP2 homodimer

Summary for 6OMN

Entry DOI	10.2210/pdb6omn/pdb
Descriptor	Bone morphogenetic protein 2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	bmp, bone mophogenetic protein, cytokine
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	52443.35
Authors	Juo, Z.S.,Seeherman, H. (deposition date: 2019-04-19, release date: 2019-05-08, Last modification date: 2020-07-29)
Primary citation	Seeherman, H.J.,Berasi, S.P.,Brown, C.T.,Martinez, R.X.,Juo, Z.S.,Jelinsky, S.,Cain, M.J.,Grode, J.,Tumelty, K.E.,Bohner, M.,Grinberg, O.,Orr, N.,Shoseyov, O.,Eyckmans, J.,Chen, C.,Morales, P.R.,Wilson, C.G.,Vanderploeg, E.J.,Wozney, J.M. A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med, 11:-, 2019 Cited by PubMed: 31019025 DOI: 10.1126/scitranslmed.aar4953 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.68 Å)

Structure validation