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Showing 1 - 50 of 55 items for (author: shoichet & b)
![](data/emdb/media/40207/emdbimg.jpg)
EMDB-40207:
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853
Method: single particle / : Liu F, Chen J
![](data/emdb/media/42676/emdbimg.jpg)
EMDB-42676:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G
![](data/emdb/media/42999/emdbimg.jpg)
EMDB-42999:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL
![](data/pdb/img/8uwl.jpg)
PDB-8uwl:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G
![](data/pdb/img/8v6u.jpg)
PDB-8v6u:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL
![](data/emdb/media/29898/emdbimg.jpg)
EMDB-29898:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK
![](data/pdb/img/8gag.jpg)
PDB-8gag:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK
![](data/emdb/media/40768/emdbimg.jpg)
EMDB-40768:
TMEM16F 1PBC
Method: single particle / : Wu H, Feng S, Cheng Y
![](data/emdb/media/40776/emdbimg.jpg)
EMDB-40776:
TMEM16F bound with Niclosamide
Method: single particle / : Feng S, Cheng Y
![](data/emdb/media/41134/emdbimg.jpg)
EMDB-41134:
TMEM16F, with Calcium and PIP2, no inhibitor
Method: single particle / : Feng S, Cheng Y
![](data/emdb/media/41136/emdbimg.jpg)
EMDB-41136:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl2
Method: single particle / : Wu H, Feng S, Cheng Y
![](data/emdb/media/41137/emdbimg.jpg)
EMDB-41137:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl1
Method: single particle / : Wu H, Feng S, Cheng Y
![](data/pdb/img/8tai.jpg)
PDB-8tai:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl2
Method: single particle / : Wu H, Feng S, Cheng Y
![](data/pdb/img/8tal.jpg)
PDB-8tal:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl1
Method: single particle / : Wu H, Feng S, Cheng Y
![](data/emdb/media/26160/emdbimg.jpg)
EMDB-26160:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl
Method: single particle / : Singh I, Seth A
![](data/pdb/img/7txt.jpg)
PDB-7txt:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl
Method: single particle / : Singh I, Seth A, Billesboelle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V, Huang XP, Boytsov D, Lak P, O'Donnell H, Sandtner W, Roth BL, Basbaum AI, Wetsel WC, Manglik A, Shoichet BK, Rudnick G
![](data/emdb/media/27752/emdbimg.jpg)
EMDB-27752:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/emdb/media/27753/emdbimg.jpg)
EMDB-27753:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/emdb/media/27754/emdbimg.jpg)
EMDB-27754:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/pdb/img/8dwc.jpg)
PDB-8dwc:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/pdb/img/8dwg.jpg)
PDB-8dwg:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/pdb/img/8dwh.jpg)
PDB-8dwh:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL
![](data/emdb/media/32331/emdbimg.jpg)
EMDB-32331:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y
![](data/emdb/media/32342/emdbimg.jpg)
EMDB-32342:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y
![](data/pdb/img/7w6p.jpg)
PDB-7w6p:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y
![](data/pdb/img/7w7e.jpg)
PDB-7w7e:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y
![](data/emdb/media/26597/emdbimg.jpg)
EMDB-26597:
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/emdb/media/26598/emdbimg.jpg)
EMDB-26598:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/emdb/media/26599/emdbimg.jpg)
EMDB-26599:
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/pdb/img/7um5.jpg)
PDB-7um5:
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/pdb/img/7um6.jpg)
PDB-7um6:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/pdb/img/7um7.jpg)
PDB-7um7:
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine
Method: single particle / : Zhang S, Fay JF, Roth BL
![](data/emdb/media/24378/emdbimg.jpg)
EMDB-24378:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G
![](data/pdb/img/7ran.jpg)
PDB-7ran:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G
![](data/emdb/media/24896/snaps2.jpg)
EMDB-24896:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/emdb/media/24897/snaps2.jpg)
EMDB-24897:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/emdb/media/24898/snaps2.jpg)
EMDB-24898:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/emdb/media/24899/snaps2.jpg)
EMDB-24899:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/emdb/media/24900/snaps2.jpg)
EMDB-24900:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/pdb/media/7s8l/snapsdep.jpg)
PDB-7s8l:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/pdb/media/7s8m/snapsdep.jpg)
PDB-7s8m:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/pdb/media/7s8n/snapsdep.jpg)
PDB-7s8n:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/pdb/media/7s8o/snapsdep.jpg)
PDB-7s8o:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/pdb/media/7s8p/snapsdep.jpg)
PDB-7s8p:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL
![](data/emdb/media/22829/snaps2.jpg)
EMDB-22829:
Human Tom70 in complex with SARS CoV2 Orf9b
Method: single particle / : QCRG Structural Biology Consortium
![](data/pdb/media/7kdt/snapsdep.jpg)
PDB-7kdt:
Human Tom70 in complex with SARS CoV2 Orf9b
Method: single particle / : QCRG Structural Biology Consortium
![](data/emdb/media/21669/snaps2.jpg)
EMDB-21669:
HTR2A bound to 25-CN-NBOH in complex with a mini-Galpha-q protein, beta/gamma subunits and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Skiniotis G, Roth B, Kim K, Panova O
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