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Showing 1 - 50 of 105 items for (author: shoichet & b)

EMDB-44865:
Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-44866:
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

PDB-9bs9:
Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

PDB-9bsb:
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-71783:
Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149
Method: single particle / : Srinivasan K, Wu Y, Billesboelle C, Kim JY, Manglik A, Shoichet BK

PDB-9pqd:
Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149
Method: single particle / : Srinivasan K, Wu Y, Billesboelle C, Kim JY, Manglik A, Shoichet BK

EMDB-71718:
Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

PDB-9pln:
Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

EMDB-71719:
Structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

PDB-9plo:
Structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)
Method: single particle / : Srinivasan K, Xu X, Mailhot O, Manglik A, Shoichet B

EMDB-51434:
Befiradol-bound serotonin 5-HT1A receptor - Gs Protein Complex
Method: single particle / : Schneider J, Gmeiner P, Boettcher B, Rasmussen T

PDB-9gl2:
Befiradol-bound serotonin 5-HT1A receptor - Gs Protein Complex
Method: single particle / : Schneider J, Gmeiner P, Boettcher B, Rasmussen T

EMDB-44945:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking local map
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-44946:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking, local refinement of heterotrimer
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-44961:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking global map
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-46828:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK

EMDB-47992:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK

PDB-9dgi:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK

PDB-9ego:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK

EMDB-48524:
Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #33
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

EMDB-48525:
Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound#020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

EMDB-48526:
Locally-refined Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

EMDB-48527:
Inactive Kappa-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

EMDB-48528:
Locally-Refined Inactive Kappa-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

PDB-9mqh:
Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #33
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

PDB-9mqi:
Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

PDB-9mqj:
Locally-refined Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

PDB-9mqk:
Inactive Kappa-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

PDB-9mql:
Locally-Refined Inactive Kappa-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
Method: single particle / : Kim JY, Vigneron SF, Billesbolle C, Manglik A, Shoichet BK

EMDB-47113:
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-2825
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

EMDB-47114:
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-3945
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

PDB-9dqh:
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-2825
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

PDB-9dqj:
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-3945
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

EMDB-45127:
Structure of Calcium-Sensing Receptor in complex with positive allosteric modulator '6218
Method: single particle / : Wu C, Skiniotis G

EMDB-45156:
Structure of Calcium-Sensing Receptor in complex with positive allosteric modulator '54149
Method: single particle / : Wu C, Skiniotis G

EMDB-45792:
Constituent EM map: focused refinement of the Venus flytrap (VFT) and cysteine-rich (CRD) domains of the calcium-sensing receptor.
Method: single particle / : Wu C, Skiniotis G

EMDB-45795:
Focused refinement of the Heptahelical transmembrane (7TM) domain of the calcium-sensing receptor
Method: single particle / : Wu C, Skiniotis G

EMDB-45804:
Raw Consensus map of the Calcium-Sensing Receptor in complex with positive allosteric modulator '6218
Method: single particle / : Wu C, Skiniotis G

EMDB-45882:
Raw Consensus map of the Calcium-Sensing Receptor in complex with positive allosteric modulator '54149
Method: single particle / : Wu C, Skiniotis G

EMDB-45901:
Focused refinement of the Heptahelical transmembrane (7TM) domain of the calcium-sensing receptor bound to positive modulator '54149
Method: single particle / : Wu C, Skiniotis G

EMDB-45902:
Focused refinement of the Venus flytrap domain of the calcium-sensing receptor bound to positive modulator '54149
Method: single particle / : Wu C, Skiniotis G

PDB-9c1p:
Structure of Calcium-Sensing Receptor in complex with positive allosteric modulator '6218
Method: single particle / : Wu C, Skiniotis G

PDB-9c2f:
Structure of Calcium-Sensing Receptor in complex with positive allosteric modulator '54149
Method: single particle / : Wu C, Skiniotis G

EMDB-42463:
Alzheimer's disease PHF complexed with PET ligand MK-6240
Method: helical / : Kunach P, Shahmoradian SH, Diamond MI, Rosa-Neto P

PDB-8uq7:
Alzheimer's disease PHF complexed with PET ligand MK-6240
Method: helical / : Kunach P, Shahmoradian SH, Diamond MI, Rosa-Neto P

EMDB-40207:
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853
Method: single particle / : Liu F, Chen J

PDB-8gls:
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853
Method: single particle / : Liu F, Chen J

EMDB-17712:
ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex
Method: single particle / : Schneider J, Gmeiner P, Rasmussen T, Boettcher B

EMDB-17747:
Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex
Method: single particle / : Schneider J, Gmeiner P, Hove TT, Rasmussen T, Boettcher B

PDB-8pjk:
ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex
Method: single particle / : Schneider J, Gmeiner P, Rasmussen T, Boettcher B

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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