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Showing 1 - 50 of 61 items for (author: kirk & ns)

EMDB-46597:
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

PDB-9d6l:
Human Sec61 complex inhibited by KZR-261
Method: single particle / : Park E, Wang L

EMDB-52520:
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

PDB-9hz5:
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
Method: single particle / : Shahid R, Paavilainen VO

EMDB-46598:
Human-yeast chimeric Sec complex bound to KZR-261 inhibitor
Method: single particle / : Park E, Wang L

EMDB-48457:
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318
Method: single particle / : Nie S

PDB-9moe:
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318
Method: single particle / : Nie S

EMDB-48083:
Import stalled PINK1 TOM complex
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-48084:
Import stalled PINK1 TOM complex, symmetry expanded
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-48085:
Import stalled PINK1 TOM complex, extended TOM20 helix class
Method: single particle / : Kirk NS, Glukhova A, Callegari S, Komander D

EMDB-19638:
YlmH bound to PtRNA-50S
Method: single particle / : Paternoga H, Dimitrova-Paternoga L, Wilson DN

EMDB-19641:
YlmH bound to stalled 50S subunits with RqcH and PtRNA
Method: single particle / : Paternoga H, Wilson DN

PDB-8s1p:
YlmH bound to PtRNA-50S
Method: single particle / : Paternoga H, Dimitrova-Paternoga L, Wilson DN

PDB-8s1u:
YlmH bound to stalled 50S subunits with RqcH and PtRNA
Method: single particle / : Paternoga H, Wilson DN

EMDB-43753:
Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Method: single particle / : Shi SS, Kuang ZL, Zhao R

PDB-8w2o:
Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Method: single particle / : Shi SS, Kuang ZL, Zhao R

EMDB-18207:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide, Glacios map
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18230:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18915:
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8q7r:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8r5h:
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-42804:
Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-42806:
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-42807:
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
Method: single particle / : Gan ZY, Kirk NS, Leis A, Komander D

EMDB-18586:
Cryo-EM reconstruction of crosslinked native Bacillus subtilis collided disome binding MutS2 SMR and KOW domains
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-41138:
CryoEM structure of MFRV-VILP bound to IGF1Rzip
Method: single particle / : Kirk NS

EMDB-18585:
Cryo-EM reconstruction of Bacillus subtilis collided disome binding MutS2 SMR and KOW domains
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-18901:
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

PDB-8r55:
Bacillus subtilis MutS2-collided disome complex (collided 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-18558:
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

PDB-8qpp:
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Method: single particle / : Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR

EMDB-29101:
EGFR:Degrader:VHL:Elongin-B/C:Cul2
Method: single particle / : Rosenberg SC

EMDB-26306:
Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form
Method: single particle / : Kirk NS, Lawrence MC

EMDB-26363:
Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM459
Method: single particle / : Kirk NS, Lawrence MC

EMDB-26364:
Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM462
Method: single particle / : Kirk NS, Lawrence MC

EMDB-24791:
Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

EMDB-24927:
Leg region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

EMDB-13957:
Extended H/L (SLPH/SLPL) complex from C. difficile (CD630 strain) fit into R20291 S-layer negative stain map
Method: electron crystallography / : Banerji O, Wilson JS

PDB-7qgq:
Extended H/L (SLPH/SLPL) complex from C. difficile (CD630 strain) fit into R20291 S-layer negative stain map
Method: electron crystallography / : Banerji O, Wilson JS, Bullough PA

EMDB-21415:
Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21416:
Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21417:
Head region of the close conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21418:
Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II
Method: single particle / : Xu Y, Kirk NS

EMDB-0360:
Saccharomyces cerevisiae spliceosomal E complex (UBC4)
Method: single particle / : Liu S, Li X

EMDB-0361:
Saccharomyces cerevisiae spliceosomal E complex (ACT1)
Method: single particle / : Liu S, Li X

PDB-6n7p:
S. cerevisiae spliceosomal E complex (UBC4)
Method: single particle / : Liu S, Li X, Zhou ZH, Zhao R

PDB-6n7r:
Saccharomyces cerevisiae spliceosomal E complex (ACT1)
Method: single particle / : Liu S, Li X, Zhou ZH, Zhao R

PDB-6n7x:
S. cerevisiae U1 snRNP
Method: single particle / : Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R

EMDB-7109:
S. cerevisiae spliceosomal post-catalytic P complex
Method: single particle / : Liu S

PDB-6bk8:
S. cerevisiae spliceosomal post-catalytic P complex
Method: single particle / : Liu S, Li X, Zhou ZH, Zhao R

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