Author results

3U2I
  • Download 3u2i
  • View 3u2i
Molmil generated image of 3u2i
X-RAY CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN AT ROOM TEMPERATURE
Descriptor:Transthyretin
Authors:Yokoyama, T., Mizuguchi, M., Nabeshima, Y., Kusaka, K., Yamada, T., Hosoya, T., Ohhara, T., Kurihara, K., Tomoyori, K., Tanaka, I., Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012
3U2J
  • Download 3u2j
  • View 3u2j
Molmil generated image of 3u2j
NEUTRON CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:Transthyretin
Authors:Yokoyama, T., Mizuguchi, M., Nabeshima, Y., Kusaka, K., Yamada, T., Hosoya, T., Ohhara, T., Kurihara, K., Tomoyori, K., Tanaka, I., Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2018-03-07
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012
6IP5
  • Download 6ip5
  • View 6ip5
Molmil generated image of 6ip5
CRYO-EM STRUCTURE OF THE CMV-STALLED HUMAN 80S RIBOSOME (STRUCTURE II)
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Yokoyama, T., Shigematsu, H., Shirouzu, M., Imataka, H., Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP6
  • Download 6ip6
  • View 6ip6
Molmil generated image of 6ip6
CRYO-EM STRUCTURE OF THE CMV-STALLED HUMAN 80S RIBOSOME WITH HCV IRES (STRUCTURE III)
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Yokoyama, T., Shigematsu, H., Shirouzu, M., Imataka, H., Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP8
  • Download 6ip8
  • View 6ip8
Molmil generated image of 6ip8
CRYO-EM STRUCTURE OF THE HCV IRES DEPENDENTLY INITIATED CMV-STALLED 80S RIBOSOME (STRUCTURE IV)
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Yokoyama, T., Shigematsu, H., Shirouzu, M., Imataka, H., Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
2D5X
  • Download 2d5x
  • View 2d5x
Molmil generated image of 2d5x
CRYSTAL STRUCTURE OF CARBONMONOXY HORSE HEMOGLOBIN COMPLEXED WITH L35
Descriptor:Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yokoyama, T., Neya, S., Tsuneshige, A., Yonetani, T., Park, S.Y., Tame, J.R.
Deposit date:2005-11-08
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35
J.Mol.Biol., 356, 2006
2D5Z
  • Download 2d5z
  • View 2d5z
Molmil generated image of 2d5z
CRYSTAL STRUCTURE OF T-STATE HUMAN HEMOGLOBIN COMPLEXED WITH THREE L35 MOLECULES
Descriptor:Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yokoyama, T., Neya, S., Tsuneshige, A., Yonetani, T., Park, S.Y., Tame, J.R.
Deposit date:2005-11-08
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35
J.Mol.Biol., 356, 2006
2D60
  • Download 2d60
  • View 2d60
Molmil generated image of 2d60
CRYSTAL STRUCTURE OF DEOXY HUMAN HEMOGLOBIN COMPLEXED WITH TWO L35 MOLECULES
Descriptor:Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yokoyama, T., Neya, S., Tsuneshige, A., Yonetani, T., Park, S.Y., Tame, J.R.
Deposit date:2005-11-08
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35
J.Mol.Biol., 356, 2006
3J0E
  • Download 3j0e
  • View 3j0e
Molmil generated image of 3j0e
MODELS FOR THE T. THERMOPHILUS RIBOSOME RECYCLING FACTOR AND THE E. COLI ELONGATION FACTOR G BOUND TO THE E. COLI POST-TERMINATION COMPLEX
Descriptor:ribosomal 23S RNA, ribosomal 16S RNA, 30S ribosomal protein S12, ...
Authors:Yokoyama, T., Shaikh, T.R., Iwakura, N., Kaji, H., Kaji, A., Agrawal, R.K.
Deposit date:2011-06-29
Release date:2012-04-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
5AYT
  • Download 5ayt
  • View 5ayt
Molmil generated image of 5ayt
CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH L6
Descriptor:Transthyretin, 2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione
Authors:Yokoyama, T., Mizuguchi, M., Kai, H.
Deposit date:2015-09-03
Release date:2016-01-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione
J. Pharmacol. Sci., 129, 2015
5H0V
  • Download 5h0v
  • View 5h0v
Molmil generated image of 5h0v
CRYSTAL STRUCTURE OF H88A MUTATED HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION
Authors:Yokoyama, T., Hanawa, Y., Obita, T., Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0W
  • Download 5h0w
  • View 5h0w
Molmil generated image of 5h0w
CRYSTAL STRUCTURE OF H88F MUTATED HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, SULFATE ION
Authors:Yokoyama, T., Hanawa, Y., Obita, T., Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0X
  • Download 5h0x
  • View 5h0x
Molmil generated image of 5h0x
CRYSTAL STRUCTURE OF H88S MUTATED HUMAN TRANSTHYRETIN
Descriptor:Transthyretin
Authors:Yokoyama, T., Hanawa, Y., Obita, T., Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0Y
  • Download 5h0y
  • View 5h0y
Molmil generated image of 5h0y
CRYSTAL STRUCTURE OF H88Y MUTATED HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, SULFATE ION, CHLORIDE ION
Authors:Yokoyama, T., Hanawa, Y., Obita, T., Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0Z
  • Download 5h0z
  • View 5h0z
Molmil generated image of 5h0z
CRYSTAL STRUCTURE OF P113A MUTATED HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, SULFATE ION, CHLORIDE ION
Authors:Yokoyama, T., Hanawa, Y., Obita, T., Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.735 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
1V4U
  • Download 1v4u
  • View 1v4u
Molmil generated image of 1v4u
CRYSTAL STRUCTURE OF BLUEFIN TUNA CARBONMONOXY-HEMOGLOBIN
Descriptor:hemoglobin alpha chain, hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yokoyama, T., Chong, K.T., Miyazaki, Y., Nakatsukasa, T., Unzai, S., Miyazaki, G., Morimoto, H., Jeremy, R.H.T., Park, S.Y.
Deposit date:2003-11-19
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel Mechanisms of pH Sensitivity in Tuna Hemoglobin: A STRUCTURAL EXPLANATION OF THE ROOT EFFECT
J.Biol.Chem., 279, 2004
1V4W
  • Download 1v4w
  • View 1v4w
Molmil generated image of 1v4w
CRYSTAL STRUCTURE OF BLUEFIN TUNA HEMOGLOBIN DEOXY FORM AT PH7.5
Descriptor:hemoglobin alpha chain, hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yokoyama, T., Chong, K.T., Miyazaki, Y., Nakatsukasa, T., Unzai, S., Miyazaki, G., Morimoto, H., Jeremy, R.H.T., Park, S.Y.
Deposit date:2003-11-19
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Novel Mechanisms of pH Sensitivity in Tuna Hemoglobin: A STRUCTURAL EXPLANATION OF THE ROOT EFFECT
J.Biol.Chem., 279, 2004
1V4X
  • Download 1v4x
  • View 1v4x
Molmil generated image of 1v4x
CRYSTAL STRUCTURE OF BLUEFIN TUNA HEMOGLOBIN DEOXY FORM AT PH5.0
Descriptor:hemoglobin alpha chain, hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yokoyama, T., Chong, K.T., Miyazaki, Y., Nakatsukasa, T., Unzai, S., Miyazaki, G., Morimoto, H., Jeremy, R.H.T., Park, S.Y.
Deposit date:2003-11-19
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Novel Mechanisms of pH Sensitivity in Tuna Hemoglobin: A STRUCTURAL EXPLANATION OF THE ROOT EFFECT
J.Biol.Chem., 279, 2004
3J0D
  • Download 3j0d
  • View 3j0d
Molmil generated image of 3j0d
MODELS FOR THE T. THERMOPHILUS RIBOSOME RECYCLING FACTOR BOUND TO THE E. COLI POST-TERMINATION COMPLEX
Descriptor:ribosomal 23S RNA, 50S ribosomal protein L11, ribosomal 16S RNA, ...
Authors:Yokoyama, T., Shaikh, T.R., Iwakura, N., Kaji, H., Kaji, A., Agrawal, R.K.
Deposit date:2011-06-29
Release date:2012-04-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11.1 Å)
Cite:Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
3BNV
  • Download 3bnv
  • View 3bnv
Molmil generated image of 3bnv
CRYSTAL STRUCTURE OF CJ0977, A SIGMA28-REGULATED VIRULENCE PROTEIN FROM CAMPYLOBACTER JEJUNI.
Descriptor:Cj0977
Authors:Yokoyama, T., Yeo, H.J.
Deposit date:2007-12-14
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a sigma28-regulated nonflagellar virulence protein from Campylobacter jejuni.
J.Mol.Biol., 384, 2008
3D6L
  • Download 3d6l
  • View 3d6l
Molmil generated image of 3d6l
CRYSTAL STRUCTURE OF CJ0915, A HEXAMERIC HOTDOG FOLD THIOESTERASE OF CAMPYLOBACTER JEJUNI
Descriptor:Putative hydrolase, CHLORIDE ION
Authors:Yokoyama, T., Yeo, H.J.
Deposit date:2008-05-19
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure and function of a Campylobacter jejuni thioesterase Cj0915, a hexameric hot dog fold enzyme.
Biochim.Biophys.Acta, 1794, 2009
4N85
  • Download 4n85
  • View 4n85
Molmil generated image of 4n85
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, CALCIUM ION
Authors:Yokoyama, T., Kosaka, Y., Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
4N86
  • Download 4n86
  • View 4n86
Molmil generated image of 4n86
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN COMPLEXED WITH GLABRIDIN
Descriptor:Transthyretin, 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, CALCIUM ION
Authors:Yokoyama, T., Kosaka, Y., Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
4N87
  • Download 4n87
  • View 4n87
Molmil generated image of 4n87
CRYSTAL STRUCTURE OF V30M MUTANT HUMAN TRANSTHYRETIN COMPLEXED WITH GLABRIDIN
Descriptor:Transthyretin, 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
Authors:Yokoyama, T., Kosaka, Y., Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
4PWE
  • Download 4pwe
  • View 4pwe
Molmil generated image of 4pwe
CRYSTAL STRUCTURE OF V30M MUTANT HUMAN TRANSTHYRETIN
Descriptor:Transthyretin
Authors:Yokoyama, T., Kosaka, Y., Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014