6IN3

Crystal structure of DOT1L in complex with 18-Crown-6

Summary for 6IN3

• Entry DOI: 10.2210/pdb6in3/pdb
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: histone h3k79 methyltransferase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 40179.37

Authors

Yokoyama, T.,Kosaka, Y.,Matsumoto, K.,Kitakami, R.,Nabeshima, Y.,Mizuguchi, M. (deposition date: 2018-10-24, release date: 2019-10-30, Last modification date: 2024-03-27)

• Primary citation: Yokoyama, T.,Kosaka, Y.,Matsumoto, K.,Kitakami, R.,Nabeshima, Y.,Mizuguchi, M.; Crown Ethers as Transthyretin Amyloidogenesis Inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)