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6IMZ

Crystal structure of MTH1 in complex with 18-Crown-6

Summary for 6IMZ
Entry DOI10.2210/pdb6imz/pdb
Descriptor7,8-dihydro-8-oxoguanine triphosphatase, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywordshuman nudix hydrolase, 8-oxo-dgtp, cancer, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight20256.82
Authors
Yokoyama, T.,Kosaka, Y.,Matsumoto, K.,Kitakami, R.,Nabeshima, Y.,Mizuguchi, M. (deposition date: 2018-10-24, release date: 2019-10-30, Last modification date: 2024-03-27)
Primary citationYokoyama, T.,Kosaka, Y.,Matsumoto, K.,Kitakami, R.,Nabeshima, Y.,Mizuguchi, M.
Crown Ethers as Transthyretin Amyloidogenesis Inhibitor
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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