3VC8 | | CRYSTAL STRUCTURE OF THE C-TERMINAL CYTOPLASMIC DOMAIN OF NON-STRUCTURAL PROTEIN 4 FROM MOUSE HEPATITIS VIRUS A59 | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Xu, X., Lou, Z., Ma, Y., Chen, X., Yang, Z., Tong, X., Zhao, Q., Xu, Y., Deng, H., Bartlam, M., Rao, Z. | | Deposit date: | 2012-01-03 | | Release date: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
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3VCB | | C425S MUTANT OF THE C-TERMINAL CYTOPLASMIC DOMAIN OF NON-STRUCTURAL PROTEIN 4 FROM MOUSE HEPATITIS VIRUS A59 | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Xu, X., Lou, Z., Ma, Y., Chen, X., Yang, Z., Tong, X., Zhao, Q., Xu, Y., Deng, H., Bartlam, M., Rao, Z. | | Deposit date: | 2012-01-03 | | Release date: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
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4OIV | | STRUCTURAL BASIS FOR SMALL MOLECULE NDB AS A SELECTIVE ANTAGONIST OF FXR | | Descriptor: | Bile acid receptor, N-benzyl-N-(3-tert-butyl-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino)benzamide | | Authors: | Xu, X., Chen, L., Hu, L., Shen, X. | | Deposit date: | 2014-01-20 | | Release date: | 2015-03-25 | | Last modified: | 2015-08-19 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
J.Biol.Chem., 290, 2015
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1T09 | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX NADP | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Xu, X., Zhao, J., Peng, B., Huang, Q., Arnold, E., Ding, J. | | Deposit date: | 2004-04-08 | | Release date: | 2004-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
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1T0L | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP, ISOCITRATE, AND CALCIUM(2+) | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Xu, X., Zhao, J., Peng, B., Huang, Q., Arnold, E., Ding, J. | | Deposit date: | 2004-04-10 | | Release date: | 2004-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
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2GTH | | CRYSTAL STRUCTURE OF THE WILDTYPE MHV CORONAVIRUS NON-STRUCTURAL PROTEIN NSP15 | | Descriptor: | Replicase polyprotein 1ab | | Authors: | Xu, X., Zhai, Y., Sun, F., Lou, Z., Su, D., Rao, Z. | | Deposit date: | 2006-04-28 | | Release date: | 2006-08-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
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2GTI | | MUTATION OF MHV CORONAVIRUS NON-STRUCTURAL PROTEIN NSP15 (F307L) | | Descriptor: | Replicase polyprotein 1ab, SULFATE ION, GLYCEROL | | Authors: | Xu, X., Zhai, Y., Sun, F., Lou, Z., Su, D., Rao, Z. | | Deposit date: | 2006-04-28 | | Release date: | 2006-08-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
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3B7E | | NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN IN COMPLEX WITH ZANAMIVIR | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ... | | Authors: | Xu, X., Zhu, X., Wilson, I.A. | | Deposit date: | 2007-10-30 | | Release date: | 2008-10-07 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
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3BEQ | | NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ... | | Authors: | Xu, X., Zhu, X., Wilson, I.A. | | Deposit date: | 2007-11-19 | | Release date: | 2008-09-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
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3W8H | |
3W8I | |
4HBN | | CRYSTAL STRUCTURE OF THE HUMAN HCN4 CHANNEL C-TERMINUS CARRYING THE S672R MUTATION | | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION | | Authors: | Xu, X., Marni, F., Wu, X., Su, Z., Musayev, F., Shrestha, S., Xie, C., Gao, W., Liu, Q., Zhou, L. | | Deposit date: | 2012-09-28 | | Release date: | 2013-01-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
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5UJI | |
5UJJ | |
1PCW | | AQUIFEX AEOLICUS KDO8PS IN COMPLEX WITH CADMIUM AND APP, A BISUBSTRATE INHIBITOR | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, 1-DEOXY-6-O-PHOSPHONO-1-[(PHOSPHONOMETHYL)AMINO]-L-THREO-HEXITOL | | Authors: | Xu, X., Wang, J., Grison, C., Petek, S., Coutrot, P., Birck, M., Woodard, R.W., Gatti, D.L. | | Deposit date: | 2003-05-17 | | Release date: | 2004-02-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase.
Drug DES.DISCOVERY, 18, 2003
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1TER | |
1ZHA | | A. AEOLICUS KDO8PS R106G MUTANT IN COMPLEX WITH PEP AND R5P | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, RIBOSE-5-PHOSPHATE, CADMIUM ION, ... | | Authors: | Xu, X., Kona, F., Wang, J., Lu, J., Stemmler, T., Gatti, D.L. | | Deposit date: | 2005-04-25 | | Release date: | 2005-09-27 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop.
Biochemistry, 44, 2005
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1ZJI | | AQUIFEX AEOLICUS KDO8PS R106G MUTANT IN COMPLEX WITH 2PGA AND R5P | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, RIBOSE-5-PHOSPHATE, CADMIUM ION, ... | | Authors: | Xu, X., Kona, F., Wang, J., Lu, J., Stemmler, T., Gatti, D.L. | | Deposit date: | 2005-04-28 | | Release date: | 2005-09-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop
Biochemistry, 44, 2005
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2JQR | | SOLUTION MODEL OF CROSSLINKED COMPLEX OF CYTOCHROME C AND ADRENODOXIN | | Descriptor: | Cytochrome c iso-1, Adrenodoxin, mitochondrial, ... | | Authors: | Xu, X., Reinle, W., Hannemann, F., Konarev, P.V., Svergun, D.I., Bernhardt, R., Ubbink, M. | | Deposit date: | 2007-06-07 | | Release date: | 2008-04-22 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy
J.Am.Chem.Soc., 130, 2008
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2KAJ | | NMR STRUCTURE OF GALLIUM SUBSTITUTED FERREDOXIN | | Descriptor: | Ferredoxin-1, GALLIUM (III) ION | | Authors: | Xu, X., Ubbink, M., Knaff, D.B. | | Deposit date: | 2008-11-06 | | Release date: | 2009-11-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structural and functional characterization of the ga-substituted ferredoxin from Synechocystis sp. PCC6803, a mimic of the native protein.
Biochemistry, 49, 2010
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2LY9 | | SOLUTION NMR STRUCTURE OF HOMEOBOX 2 DOMAIN FROM HUMAN ZHX1 REPRESSOR, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR7907F | | Descriptor: | Zinc fingers and homeoboxes protein 1 | | Authors: | Xu, X., Eletsky, A., Mills, J.L., Pulavarti, S.V.S.R.K., Lee, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-09-14 | | Release date: | 2012-11-14 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F
To be Published
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2M0C | | SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN OF HUMAN ALX4, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4490C | | Descriptor: | Homeobox protein aristaless-like 4 | | Authors: | Xu, X., Eletsky, A., Pulavarti, S., Lee, D., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-10-24 | | Release date: | 2012-11-21 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
To be Published
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2M9W | | SOLUTION NMR STRUCTURE OF TRANSCRIPTION FACTOR GATA-4 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4783B | | Descriptor: | Transcription factor GATA-4, ZINC ION | | Authors: | Xu, X., Eletsky, A., Lee, D., Kohn, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-06-20 | | Release date: | 2013-07-10 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of a Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B
To be Published
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2M9X | | SOLUTION NMR STRUCTURE OF MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 1 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR9151A | | Descriptor: | Microtubule-associated serine/threonine-protein kinase 1 | | Authors: | Xu, X., Eletsky, A., Shastry, R., Lee, D., Hamilton, K., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-06-20 | | Release date: | 2013-07-10 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Microtubule-associated serine/threonine-protein kinase 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9151A
To be Published
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2MIO | | SOLUTION NMR STRUCTURE OF SH3 DOMAIN 1 OF RHO GTPASE-ACTIVATING PROTEIN 10 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR9129A | | Descriptor: | Rho GTPase-activating protein 10 | | Authors: | Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-12-16 | | Release date: | 2014-01-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A
To be Published
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