7BTS

Structure of human beta1 adrenergic receptor bound to epinephrine and nanobody 6B9

Summary for 7BTS

Entry DOI	10.2210/pdb7bts/pdb
Descriptor	Lysozyme-Beta-1 adrenergic receptor chimera, Camelid Antibody Fragment, L-EPINEPHRINE, ... (8 entities in total)
Functional Keywords	g protein coupled receptor, membrane protein
Biological source	Enterobacteria phage T4 More
Total number of polymer chains	2
Total formula weight	66893.22
Authors	Xu, X.,Kaindl, J.,Clark, M.,Hubner, H.,Hirata, K.,Sunahara, R.,Gmeiner, P.,Kobilka, B.K.,Liu, X. (deposition date: 2020-04-02, release date: 2020-12-02, Last modification date: 2023-11-29)
Primary citation	Xu, X.,Kaindl, J.,Clark, M.J.,Hubner, H.,Hirata, K.,Sunahara, R.K.,Gmeiner, P.,Kobilka, B.K.,Liu, X. Binding pathway determines norepinephrine selectivity for the human beta 1 AR over beta 2 AR. Cell Res., 31:569-579, 2021 Cited by PubMed: 33093660 DOI: 10.1038/s41422-020-00424-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.13 Å)

Structure validation