7BTS
Structure of human beta1 adrenergic receptor bound to epinephrine and nanobody 6B9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysozyme-Beta-1 adrenergic receptor chimera | polymer | 462 | 52235.9 | 1 | UniProt (D9IEF7) Pfam (PF00001) UniProt (by SIFTS) (P08588) | Enterobacteria phage T4 | Lysis protein,Lysozyme,Muramidase |
| 2 | B (B) | Camelid Antibody Fragment | polymer | 120 | 12949.4 | 1 | Vicugna pacos (Alpaca) | ||
| 3 | C (A) | L-EPINEPHRINE | non-polymer | 183.2 | 1 | Chemie (ALE) | |||
| 4 | D, E, F, G, H... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | J (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 6 | K (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) PubChem (23831) | |||
| 7 | L (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (304) PubChem (176980071) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (18640088) PubChem (1715243) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (1715244) PubChem (23423981) PubChem (45044259) PubChem (638019) PubChem (49853509) PubChem (50990013) PubChem (44654663) PubChem (52934537) PubChem (56621683) PubChem (1549081) PubChem (1553803) PubChem (46937002) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (59274407) PubChem (5283629) PubChem (5284644) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (5315842) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (6419195) PubChem (5997) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (1551269) PubChem (90070115) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (117965027) PubChem (6432564) PubChem (101624109) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (124225449) PubChem (124429284) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (138967089) PubChem (139566851) PubChem (130459183) PubChem (131992107) PubChem (15939944) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (171828367) PubChem (173516975) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 8 | M (A) | (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate | non-polymer | 300.4 | 1 | Chemie (1WV) |
Sequence modifications
A: 892 - 1051 (UniProt: D9IEF7)
A: 1054 - 1399 (PDB: 7BTS)
| PDB | External Database | Details |
|---|---|---|
| Asp 884 | - | expression tag |
| Tyr 885 | - | expression tag |
| Lys 886 | - | expression tag |
| Asp 887 | - | expression tag |
| Asp 888 | - | expression tag |
| Asp 889 | - | expression tag |
| Asp 890 | - | expression tag |
| Ala 891 | - | expression tag |
| Thr 944 | Cys 54 | engineered mutation |
| Ala 987 | Cys 97 | engineered mutation |
| Ala 1052 | - | linker |
| Ala 1053 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65185.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1708.0 | |
| All* | Total formula weight | 66893.2 |
