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7BVQ

Structure of human beta1 adrenergic receptor bound to carazolol

Summary for 7BVQ
Entry DOI10.2210/pdb7bvq/pdb
Related PRD IDPRD_900001
DescriptorEndolysin,Beta-1 adrenergic receptor chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CHOLESTEROL, ... (10 entities in total)
Functional Keywordsg protein coupled receptor, membrane protein, signaling protein
Biological sourceEnterobacteria phage T4
More
Total number of polymer chains2
Total formula weight108350.98
Authors
Xu, X.,Kaindl, J.,Clark, M.,Hubner, H.,Hirata, K.,Sunahara, R.,Gmeiner, P.,Kobilka, B.K.,Liu, X. (deposition date: 2020-04-11, release date: 2020-12-02, Last modification date: 2023-11-29)
Primary citationXu, X.,Kaindl, J.,Clark, M.J.,Hubner, H.,Hirata, K.,Sunahara, R.K.,Gmeiner, P.,Kobilka, B.K.,Liu, X.
Binding pathway determines norepinephrine selectivity for the human beta 1 AR over beta 2 AR.
Cell Res., 31:569-579, 2021
Cited by
PubMed: 33093660
DOI: 10.1038/s41422-020-00424-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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