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6FAI
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BU of 6fai by Molmil
Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit
Descriptor: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Scaiola, A, Pena, C, Weisser, M, Boehringer, D, Leibundgut, M, Klingauf-Nerurkar, P, Gerhardy, S, Panse, V.G, Ban, N.
Deposit date:2017-12-15
Release date:2018-02-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
EMBO J., 37, 2018
6QUL
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BU of 6qul by Molmil
Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Scaiola, A, Leibundgut, M, Boehringer, D, Ritz, D.
Deposit date:2019-02-27
Release date:2019-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic.
Sci Rep, 9, 2019
6ZWO
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BU of 6zwo by Molmil
cryo-EM structure of human mTOR complex 2, focused on one half
Descriptor: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
Deposit date:2020-07-28
Release date:2020-11-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
6ZWM
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BU of 6zwm by Molmil
cryo-EM structure of human mTOR complex 2, overall refinement
Descriptor: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
Deposit date:2020-07-28
Release date:2020-11-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
9F1C
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BU of 9f1c by Molmil
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Yudin, D, Scaiola, A, Ban, N.
Deposit date:2024-04-18
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 2024
9F1B
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BU of 9f1b by Molmil
Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Yudin, D, Scaiola, A, Ban, N.
Deposit date:2024-04-18
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 2024
9F1D
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BU of 9f1d by Molmil
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Yudin, D, Scaiola, A, Ban, N.
Deposit date:2024-04-18
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 2024
7O7Z
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BU of 7o7z by Molmil
Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7O81
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BU of 7o81 by Molmil
Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7O7Y
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BU of 7o7y by Molmil
Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7O80
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BU of 7o80 by Molmil
Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7ODS
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BU of 7ods by Molmil
State B of the human mitoribosomal large subunit assembly intermediate
Descriptor: 16S mitochondrial rRNA, DNA (30-MER),16S mitochondrial rRNA, 39S ribosomal protein L10, ...
Authors:Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N.
Deposit date:2021-04-30
Release date:2021-06-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
7ODT
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BU of 7odt by Molmil
State C of the human mitoribosomal large subunit assembly intermediate
Descriptor: 16S mitochondrial rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N.
Deposit date:2021-04-30
Release date:2021-06-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
7ODR
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BU of 7odr by Molmil
State A of the human mitoribosomal large subunit assembly intermediate
Descriptor: 16S mitochondrial rRNA, DNA (31-MER),16S mitochondrial rRNA, 39S ribosomal protein L10, ...
Authors:Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N.
Deposit date:2021-04-30
Release date:2021-06-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
6SG9
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BU of 6sg9 by Molmil
Head domain of the mt-SSU assemblosome from Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-18
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
6SGA
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BU of 6sga by Molmil
Body domain of the mt-SSU assemblosome from Trypanosoma brucei
Descriptor: 9S rRNA, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-18
Last modified:2019-09-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
7QWR
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BU of 7qwr by Molmil
Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC
Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
7QWS
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BU of 7qws by Molmil
Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
7QWQ
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BU of 7qwq by Molmil
Ternary complex of ribosome nascent chain with SRP and NAC
Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E.
Deposit date:2022-01-25
Release date:2022-03-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
6ZOK
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BU of 6zok by Molmil
SARS-CoV-2-Nsp1-40S complex, focused on body
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
Authors:Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M, Thiel, V, Muehlemann, O, Ban, N.
Deposit date:2020-07-07
Release date:2020-07-29
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27, 2020
6ZOJ
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BU of 6zoj by Molmil
SARS-CoV-2-Nsp1-40S complex, composite map
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N.
Deposit date:2020-07-07
Release date:2020-07-22
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27, 2020
6ZOL
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BU of 6zol by Molmil
SARS-CoV-2-Nsp1-40S complex, focused on head
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
Authors:Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N.
Deposit date:2020-07-07
Release date:2020-07-22
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27, 2020
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8PPK
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BU of 8ppk by Molmil
Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023

 

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