7QWS
Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC
This is a non-PDB format compatible entry.
Summary for 7QWS
Entry DOI | 10.2210/pdb7qws/pdb |
EMDB information | 14193 |
Descriptor | Nascent chain tubulin beta, Ribosomal_L18_c domain-containing protein, Ribosomal protein L32, ... (51 entities in total) |
Functional Keywords | ribosome, srp, nac, nascent chain, co-translational, endoplasmic reticulum, co-translational protein targeting, co-translational folding |
Biological source | Homo sapiens More |
Total number of polymer chains | 49 |
Total formula weight | 2592406.85 |
Authors | Jomaa, A.,Gamerdinger, M.,Hsieh, H.,Wallisch, A.,Chandrasekaran, V.,Ulusoy, Z.,Scaiola, A.,Hegde, R.,Shan, S.,Ban, N.,Deuerling, E. (deposition date: 2022-01-25, release date: 2022-03-09, Last modification date: 2024-07-17) |
Primary citation | Jomaa, A.,Gamerdinger, M.,Hsieh, H.H.,Wallisch, A.,Chandrasekaran, V.,Ulusoy, Z.,Scaiola, A.,Hegde, R.S.,Shan, S.O.,Ban, N.,Deuerling, E. Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375:839-844, 2022 Cited by PubMed: 35201867DOI: 10.1126/science.abl6459 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report