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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7QWS

Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(s)		Nascent chain tubulin betapolymer242060.51Homo sapiens
2B
(t)		Nascent polypeptide-associated complex subunit alphapolymer21523406.81UniProt (Q13765)
Pfam (PF01849)
Pfam (PF19026)		Oryctolagus cuniculus (rabbit)NAC-alpha,Alpha-NAC
3C
(u)		Transcription factor BTF3polymer16217724.01UniProt (G1TKK2)
Pfam (PF01849)		Oryctolagus cuniculus (rabbit)NacB
4D
(A)		60S ribosomal protein L8polymer24526701.31UniProt (A0A5F9D5B2)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)
5E
(b)		60S ribosomal protein L29polymer22324608.21UniProt (G1TN82)
Pfam (PF01779)
UniProt (by SIFTS) (G1SGR6)		Oryctolagus cuniculus (rabbit)
6F
(B)		Ribosomal protein L3polymer40346108.01UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)uL3
7G
(c)		60S ribosomal protein L30polymer11512821.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
8H
(C)		60S ribosomal protein L4polymer41346388.91UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)
9I
(d)		Ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
10J
(D)		Ribosomal_L18_c domain-containing proteinpolymer29734481.81UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)		Oryctolagus cuniculus (rabbit)
11K
(e)		Ribosomal protein L32polymer15718350.01UniProt (G1TUN8)
Pfam (PF01655)		Oryctolagus cuniculus (rabbit)eL32
12L
(E)		60S ribosomal protein L6polymer29133055.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
13M
(f)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
14N
(F)		uL30polymer22526662.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)		Oryctolagus cuniculus (rabbit)
15O
(g)		60S ribosomal protein L34polymer12914557.51UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)		Oryctolagus cuniculus (rabbit)
16P
(G)		60S ribosomal protein L7apolymer31936267.61UniProt (G1STW0)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
17Q
(h)		60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
18R
(H)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
19S
(i)		60S ribosomal protein L36polymer10211888.41UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
20T
(I)		60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10 (Predicted)
21U
(j)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
22V
(J)		Ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
23W
(k)		Ribosomal protein L38polymer698107.81Oryctolagus cuniculus (rabbit)
24X
(L)		Ribosomal protein L13polymer21024216.51Oryctolagus cuniculus (rabbit)
25Y
(l)		Ribosomal protein L39polymer516426.81UniProt (G1SYU7)
Pfam (PF00832)		Oryctolagus cuniculus (rabbit)eL39
26Z
(M)		60S ribosomal protein L14polymer21823810.41UniProt (U3KNW6)
Pfam (PF01929)
UniProt (by SIFTS) (G1SZ12)		Oryctolagus cuniculus (rabbit)
27AA
(m)		Ribosomal protein L40polymer12814758.41Oryctolagus cuniculus (rabbit)
28BA
(N)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
29CA
(n)		60s ribosomal protein l41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)eL41
30DA
(O)		Ribosomal protein L13apolymer50056501.61Oryctolagus cuniculus (rabbit)
31EA
(o)		eL42polymer14116130.21UniProt (A0A5F9D391)
Pfam (PF00935)		Oryctolagus cuniculus (rabbit)
32FA
(P)		60S ribosomal protein L17polymer15317758.71Oryctolagus cuniculus (rabbit)
33GA
(p)		eL43polymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)
34HA
(Q)		Ribosomal protein L18polymer18721457.41Oryctolagus cuniculus (rabbit)
35IA
(r)		60S ribosomal protein L28polymer13715783.61UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)eL28
36JA
(R)		60S ribosomal protein L19polymer19623535.31UniProt (Q3T0W9)
Pfam (PF01280)		Oryctolagus cuniculus (rabbit)eL19
37KA
(S)		Ribosomal protein L18apolymer17520696.41Oryctolagus cuniculus (rabbit)
38LA
(T)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
39MA
(U)		Ribosomal protein L22polymer10512209.01Oryctolagus cuniculus (rabbit)
40NA
(V)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
41OA
(W)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)eL24
42PA
(5)		28S rRNApolymer47541539032.01Oryctolagus cuniculus (rabbit)
43QA
(X)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
44RA
(7)		5S rRNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
45SA
(Y)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
46TA
(8)		5.8S rRNApolymer15650143.61GenBank (4CXE_3)Oryctolagus cuniculus (rabbit)
47UA
(K)		Tetratricopeptide repeat protein 5polymer44048988.41UniProt (Q8N0Z6)
Pfam (PF16669)		Homo sapiens (human)TPR repeat protein 5,Stress-responsive activator of p300,Strap
48VA
(Z)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
49WA
(a)		60S ribosomal protein L27apolymer14816620.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)uL15
50AB, BB, XA, YA, ZA
(o, p, g, j, m)		ZINC IONnon-polymer65.45Chemie (ZN)
51AC, AD, AE, BC, BD...
(5)		MAGNESIUM IONnon-polymer24.397Chemie (MG)
Sequence modifications
A: 1 - 245 (UniProt: A0A5F9D5B2)
PDBExternal DatabaseDetails
Lys 46-insertion
Asp 47-insertion
Ile 48-insertion
Ile 49-insertion
His 50-insertion
Asp 51-insertion
Pro 52-insertion
Gly 53-insertion
Arg 54-insertion
Gly 55-insertion
Ala 56-insertion
Pro 57-insertion
Leu 58-insertion
Ala 59-insertion
Lys 60-insertion
Val 61-insertion
Val 62-insertion
Phe 63-insertion
Arg 64-insertion
Asp 65-insertion
Pro 66-insertion
Tyr 67-insertion
Arg 68-insertion
Phe 69-insertion
c: 1 - 115 (UniProt: G1TDL2)
PDBExternal DatabaseDetails
Thr 34Ser 34conflict
E: -5 - 284 (UniProt: G1SKF7)
PDBExternal DatabaseDetails
Arg 126Lys 133conflict
Gln 217Lys 224conflict
F: 26 - 250 (UniProt: G1SV32)
PDBExternal DatabaseDetails
Ala 175Thr 174conflict
Gly 185Asn 184conflict
Arg 202His 201conflict
Glu 233Gly 232conflict
a: 2 - 148 (UniProt: G1SNY0)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains49
Total formula weight2589722.2
Non-Polymers*Number of molecules102
Total formula weight2684.6
All*Total formula weight2592406.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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