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6ZOK

SARS-CoV-2-Nsp1-40S complex, focused on body

Summary for 6ZOK
Entry DOI10.2210/pdb6zok/pdb
EMDB information11321
Descriptor18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... (24 entities in total)
Functional Keywordsinhibitor, mrna channel, 40s ribosomal subunit, translation
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains22
Total formula weight1000221.22
Authors
Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.-A.,Leibundgut, M.,Thiel, V.,Muehlemann, O.,Ban, N. (deposition date: 2020-07-07, release date: 2020-07-29, Last modification date: 2021-02-10)
Primary citationSchubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.A.,Leibundgut, M.,Thiel, V.,Muhlemann, O.,Ban, N.
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27:959-966, 2020
Cited by
PubMed: 32908316
DOI: 10.1038/s41594-020-0511-8
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.8 Å)
Structure validation

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