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6ZOJ

SARS-CoV-2-Nsp1-40S complex, composite map

Summary for 6ZOJ
Entry DOI10.2210/pdb6zoj/pdb
EMDB information11320
Descriptor18S ribosomal RNA, 40S ribosomal protein S8, 40S ribosomal protein S9, ... (38 entities in total)
Functional Keywordsinhibitor, mrna channel, 40s ribosomal subunit, translation
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains36
Total formula weight1236182.05
Authors
Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.-A.,Leibundgut, M.L.,Thiel, V.,Muehlemann, O.,Ban, N. (deposition date: 2020-07-07, release date: 2020-07-22, Last modification date: 2021-02-10)
Primary citationSchubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.A.,Leibundgut, M.,Thiel, V.,Muhlemann, O.,Ban, N.
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Nat.Struct.Mol.Biol., 27:959-966, 2020
Cited by
PubMed: 32908316
DOI: 10.1038/s41594-020-0511-8
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.8 Å)
Structure validation

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