8PPK
Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit
Summary for 8PPK
Entry DOI | 10.2210/pdb8ppk/pdb |
Related | 8PPL |
EMDB information | 17804 |
Descriptor | Eukaryotic translation initiation factor 1, 40S ribosomal protein S7, 40S ribosomal protein S8, ... (40 entities in total) |
Functional Keywords | nsp1, mers, sars, sars-cov2, ribosome, 40s ribosomal subunit, translation inhibition, coronavirus, 43s pic, 43s pre-initiation complex, mrna channel, initiation factor, eif2, eif3, eif1, eif1a, viral protein, translation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 37 |
Total formula weight | 1271012.02 |
Authors | Schubert, K.,Karousis, E.D.,Ban, I.,Lapointe, C.P.,Leibundgut, M.,Baeumlin, E.,Kummerant, E.,Scaiola, A.,Schoenhut, T.,Ziegelmueller, J.,Puglisi, J.D.,Muehlemann, O.,Ban, N. (deposition date: 2023-07-07, release date: 2023-10-18, Last modification date: 2024-04-24) |
Primary citation | Schubert, K.,Karousis, E.D.,Ban, I.,Lapointe, C.P.,Leibundgut, M.,Baumlin, E.,Kummerant, E.,Scaiola, A.,Schonhut, T.,Ziegelmuller, J.,Puglisi, J.D.,Muhlemann, O.,Ban, N. Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83:3546-3557.e8, 2023 Cited by PubMed: 37802027DOI: 10.1016/j.molcel.2023.09.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.98 Å) |
Structure validation
Download full validation report