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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8PPK

Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1pEukaryotic translation initiation factor 1polymer11312752.51UniProt (P41567)
Pfam (PF01253)
In PDB		Homo sapiens (human)eIF1,A121,Protein translation factor SUI1 homolog,Sui1iso1
2218S rRNApolymer1869603609.21Homo sapiens
3A40S ribosomal protein SApolymer29532926.01UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
4B40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
5C40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
6D40S ribosomal protein S3polymer24326729.41UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS3
7E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
In PDB		Homo sapiens (human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
8F40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS7
9G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
10H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS7
11I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS8
12J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS4
13K40S ribosomal protein S10polymer16518933.81UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS10
14L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS17
15M40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS12
16N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS15
17O40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS11
18P40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (human)RIG protein,Small ribosomal subunit protein uS19
19Q40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS9
20R40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS17
21SSmall ribosomal subunit protein uS13polymer15217801.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (human)40S ribosomal protein S18,Ke-3,Ke3
22TSmall ribosomal subunit protein eS19polymer14516104.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (human)40S ribosomal protein S19
23U40S ribosomal protein S20polymer11913398.81UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS10
24V40S ribosomal protein S21polymer839166.41UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS21
25W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS8
26X40S ribosomal protein S23polymer14315860.71UniProt (A0A4W2DI10)
Pfam (PF00164)
UniProt (by SIFTS) (P62266)
In PDB		Homo sapiens (human)
27Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS24
28Z40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS25
29a40S ribosomal protein S26polymer11513047.51UniProt (P62854)
Pfam (PF01283)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS26
30b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
31c40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS28
32d40S ribosomal protein S29polymer566690.81UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS14
33eSmall ribosomal subunit protein eS30polymer13314415.71UniProt (P62861)
Pfam (PF00240)
Pfam (PF04758)
In PDB		Homo sapiens (human)40S ribosomal protein S30
34fUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (human)Ubiquitin carboxyl extension protein 80
35gReceptor of activated protein C kinase 1polymer31735115.71UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
36h60S ribosomal protein L41polymer253473.51UniProt (P62945)
Pfam (PF05162)
In PDB		Homo sapiens (human)HG12,Large ribosomal subunit protein eL41
37jNsp1polymer18821172.91UniProt (A0A088DIE1)
Pfam (PF11501)
In PDB		Bat Hp-betacoronavirus/Zhejiang2013
382, N, O, X, G...UNKNOWN ATOM OR IONnon-polymer117Chemie (UNX)
392, XMAGNESIUM IONnon-polymer24.3111Chemie (MG)
40a, d, fZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
O: 1 - 151 (UniProt: P62263)
PDBExternal DatabaseDetails
Ias 138Asp 138modified residue
j: 1 - 174 (UniProt: A0A088DIE1)
PDBExternal DatabaseDetails
Met -13-initiating methionine
His -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
His -8-expression tag
His -7-expression tag
Glu -6-expression tag
Asn -5-expression tag
Leu -4-expression tag
Tyr -3-expression tag
Phe -2-expression tag
Gln -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains37
Total formula weight1268117.9
Non-Polymers*Number of molecules231
Total formula weight2894.1
All*Total formula weight1271012.0
*Water molecules are not included.

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PDB entries from 2024-08-14

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