5CYW | | CRYSTAL STRUCTURE OF VACCINIA VIRUS C7 | | Descriptor: | Interferon antagonist C7, GLYCEROL | | Authors: | Krumm, B.E., Meng, X., Li, Y., Xiang, Y., Deng, J. | | Deposit date: | 2015-07-30 | | Release date: | 2015-11-18 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5CZ3 | | CRYSTAL STRUCTURE OF MYXOMA VIRUS M64 | | Descriptor: | M64R, BETA-MERCAPTOETHANOL | | Authors: | Krumm, B.E., Meng, X., Li, Y., Xiang, Y., Deng, J. | | Deposit date: | 2015-07-31 | | Release date: | 2015-11-18 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4W60 | | THE STRUCTURE OF VACCINA VIRUS H7 PROTEIN DISPLAYS A NOVEL PHOSPHOINOSITIDE BINDING FOLD REQUIRED FOR MEMBRANE BIOGENESIS | | Descriptor: | Late protein H7 | | Authors: | Kolli, S., Meng, X., Wu, X., Shengjuler, D., Cameron, C.E., Xiang, Y., Deng, J. | | Deposit date: | 2014-08-19 | | Release date: | 2014-12-31 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
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6CMO | | RHODOPSIN-GI COMPLEX | | Descriptor: | chimera protein of Soluble cytochrome b562 and Rhodopsin, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Kang, Y., Kuybeda, O., de Waal, P.W., Mukherjee, S., Van Eps, N., Dutka, P., Zhou, X.E., Bartesaghi, A., Erramilli, S., Morizumi, T., Gu, X., Yin, Y., Liu, P., Jiang, Y., Meng, X., Zhao, G., Melcher, K., Earnst, O.P., Kossiakoff, A.A., Subramaniam, S., Xu, H.E. | | Deposit date: | 2018-03-05 | | Release date: | 2018-06-20 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
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6OMM | | CRYO-EM STRUCTURE OF FORMYL PEPTIDE RECEPTOR 2/LIPOXIN A4 RECEPTOR IN COMPLEX WITH GI | | Descriptor: | N-formyl peptide receptor 2, Peptide agonist, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Zhuang, Y., Liu, H., de Waal, P.W., Zhou, X.E., Wang, L., Meng, X., Zhao, G., Kang, Y., Melcher, K., Xu, H.E., Zhang, C. | | Deposit date: | 2019-04-19 | | Release date: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling.
Nat Commun, 11, 2020
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3J34 | | STRUCTURE OF HIV-1 CAPSID PROTEIN BY CRYO-EM | | Descriptor: | capsid protein | | Authors: | Zhao, G., Perilla, J.R., Yufenyuy, E., Meng, X., Chen, B., Ning, J., Ahn, J., Gronenborn, A.M., Schulten, K., Aiken, C., Zhang, P. | | Deposit date: | 2013-02-23 | | Release date: | 2013-05-29 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
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3J4F | | STRUCTURE OF HIV-1 CAPSID PROTEIN BY CRYO-EM | | Descriptor: | capsid protein | | Authors: | Zhao, G., Perilla, J.R., Meng, X., Schulten, K., Zhang, P. | | Deposit date: | 2013-07-11 | | Release date: | 2013-07-24 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
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4XFS | | STRUCTURE OF IL-18 SER MUTANT I | | Descriptor: | Interleukin-18, DIMETHYL SULFOXIDE, GLYCEROL | | Authors: | Krumm, B.E., Meng, X., Xiang, Y., Deng, J. | | Deposit date: | 2014-12-28 | | Release date: | 2015-06-10 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
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4XFT | | STRUCTURE OF IL-18 SER MUTANT III | | Descriptor: | Interleukin-18, DIMETHYL SULFOXIDE | | Authors: | Krumm, B.E., Meng, X., Xiang, Y., Deng, J. | | Deposit date: | 2014-12-29 | | Release date: | 2015-06-10 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
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4XFU | | STRUCTURE OF IL-18 SER MUTANT V | | Descriptor: | Interleukin-18 | | Authors: | Krumm, B.E., Meng, X., Xiang, Y., Deng, J. | | Deposit date: | 2014-12-29 | | Release date: | 2015-06-10 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
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6PT0 | | CRYO-EM STRUCTURE OF HUMAN CANNABINOID RECEPTOR 2-GI PROTEIN IN COMPLEX WITH AGONIST WIN 55,212-2 | | Descriptor: | Cannabinoid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, T.H., Xing, C., Zhuang, Y., Feng, Z., Zhou, X.E., Chen, M., Wang, L., Meng, X., Xue, Y., Wang, J., Liu, H., McGuire, T., Zhao, G., Melcher, K., Zhang, C., Xu, H.E., Xie, X.Q. | | Deposit date: | 2019-07-14 | | Release date: | 2020-02-12 | | Last modified: | 2020-03-04 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Cell, 180, 2020
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5YGI | |
5GQH | | CRYO-EM STRUCTURE OF PAECAS3-ACRF3 COMPLEX | | Descriptor: | CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3 | | Authors: | Zhang, X., Ma, J., Wang, Y., Wang, J. | | Deposit date: | 2016-08-07 | | Release date: | 2016-09-21 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
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4W5X | |
4WUM | |
5GNF | | CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF3 | | Descriptor: | Uncharacterized protein AcrF3, CALCIUM ION | | Authors: | Wang, J., Wang, Y. | | Deposit date: | 2016-07-20 | | Release date: | 2016-09-21 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
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5IMX | |
5JLJ | | CRYSTAL STRUCTURE OF KPT8602 IN COMPLEX WITH CRM1-RAN-RANBP1 | | Descriptor: | GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... | | Authors: | Fung, H.Y., Chook, Y.M. | | Deposit date: | 2016-04-27 | | Release date: | 2016-06-29 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Leukemia, 30, 2016
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6J0V | | CRYSTAL STRUCTURE OF YEAST RTT107 | | Descriptor: | Regulator of Ty1 transposition protein 107 | | Authors: | Wan, B., Wu, J., Lei, M. | | Deposit date: | 2018-12-27 | | Release date: | 2019-08-14 | | Last modified: | 2020-02-26 | | Method: | X-RAY DIFFRACTION (2.314 Å) | | Cite: | Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
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6J0W | | CRYSTAL STRUCTURE OF YEAST RTT107 AND NSE6 | | Descriptor: | Regulator of Ty1 transposition protein 107, Peptide from DNA repair protein KRE29 | | Authors: | Wan, B., Wu, J., Lei, M. | | Deposit date: | 2018-12-27 | | Release date: | 2019-08-14 | | Last modified: | 2020-02-26 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
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6J0X | | CRYSTAL STRUCTURE OF YEAST RTT107 AND MMS22 | | Descriptor: | Regulator of Ty1 transposition protein 107, Peptide from E3 ubiquitin-protein ligase substrate receptor MMS22 | | Authors: | Wan, B., Wu, J., Lei, M. | | Deposit date: | 2018-12-27 | | Release date: | 2019-08-14 | | Last modified: | 2020-02-26 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
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6J0Y | | CRYSTAL STRUCTURE OF YEAST RTT107 AND SLX4 | | Descriptor: | Regulator of Ty1 transposition protein 107, Peptide from Structure-specific endonuclease subunit SLX4 | | Authors: | Wan, B., Wu, J., Lei, M. | | Deposit date: | 2018-12-27 | | Release date: | 2019-08-14 | | Last modified: | 2020-02-26 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
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6WF3 | | CRYSTAL STRUCTURE OF HUMAN NAA50 IN COMPLEX WITH A COFACTOR DERIVED INHIBITOR (COMPOUND 1) | | Descriptor: | N-alpha-acetyltransferase 50, ACE-MET-LEU-GLY-PRO-NH2, COENZYME A | | Authors: | Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E. | | Deposit date: | 2020-04-03 | | Release date: | 2020-07-01 | | Method: | X-RAY DIFFRACTION (2.291 Å) | | Cite: | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
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6WF5 | | CRYSTAL STRUCTURE OF HUMAN NAA50 IN COMPLEX WITH A TRUNCATED COFACTOR DERIVED INHIBITOR (COMPOUND 2) | | Descriptor: | N-alpha-acetyltransferase 50, ACE-MET-LEU-GLY-PRO-NH2, (2R)-2-hydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide | | Authors: | Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E. | | Deposit date: | 2020-04-03 | | Release date: | 2020-07-01 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
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6WFG | | CRYSTAL STRUCTURE OF HUMAN NAA50 IN COMPLEX WITH AN INHIBITOR (COMPOUND 3) IDENTIFIED USING DNA ENCODED LIBRARY TECHNOLOGY | | Descriptor: | N-alpha-acetyltransferase 50, COENZYME A, (2S)-N-[(2S)-3-[1-(3-tert-butyl-1-methyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1-(methylamino)-1-oxopropan-2-yl]-6-oxopiperidine-2-carboxamide | | Authors: | Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E. | | Deposit date: | 2020-04-03 | | Release date: | 2020-07-01 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
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