Author results

5CYW
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CRYSTAL STRUCTURE OF VACCINIA VIRUS C7
Descriptor:Interferon antagonist C7, GLYCEROL
Authors:Krumm, B.E., Meng, X., Li, Y., Xiang, Y., Deng, J.
Deposit date:2015-07-30
Release date:2015-11-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CZ3
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CRYSTAL STRUCTURE OF MYXOMA VIRUS M64
Descriptor:M64R, BETA-MERCAPTOETHANOL
Authors:Krumm, B.E., Meng, X., Li, Y., Xiang, Y., Deng, J.
Deposit date:2015-07-31
Release date:2015-11-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
4W60
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THE STRUCTURE OF VACCINA VIRUS H7 PROTEIN DISPLAYS A NOVEL PHOSPHOINOSITIDE BINDING FOLD REQUIRED FOR MEMBRANE BIOGENESIS
Descriptor:Late protein H7
Authors:Kolli, S., Meng, X., Wu, X., Shengjuler, D., Cameron, C.E., Xiang, Y., Deng, J.
Deposit date:2014-08-19
Release date:2014-12-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
6CMO
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RHODOPSIN-GI COMPLEX
Descriptor:chimera protein of Soluble cytochrome b562 and Rhodopsin, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Kang, Y., Kuybeda, O., de Waal, P.W., Mukherjee, S., Van Eps, N., Dutka, P., Zhou, X.E., Bartesaghi, A., Erramilli, S., Morizumi, T., Gu, X., Yin, Y., Liu, P., Jiang, Y., Meng, X., Zhao, G., Melcher, K., Earnst, O.P., Kossiakoff, A.A., Subramaniam, S., Xu, H.E.
Deposit date:2018-03-05
Release date:2018-06-20
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
3J34
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STRUCTURE OF HIV-1 CAPSID PROTEIN BY CRYO-EM
Descriptor:capsid protein
Authors:Zhao, G., Perilla, J.R., Yufenyuy, E., Meng, X., Chen, B., Ning, J., Ahn, J., Gronenborn, A.M., Schulten, K., Aiken, C., Zhang, P.
Deposit date:2013-02-23
Release date:2013-05-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3J4F
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STRUCTURE OF HIV-1 CAPSID PROTEIN BY CRYO-EM
Descriptor:capsid protein
Authors:Zhao, G., Perilla, J.R., Meng, X., Schulten, K., Zhang, P.
Deposit date:2013-07-11
Release date:2013-07-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
4XFS
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STRUCTURE OF IL-18 SER MUTANT I
Descriptor:Interleukin-18, DIMETHYL SULFOXIDE, GLYCEROL
Authors:Krumm, B.E., Meng, X., Xiang, Y., Deng, J.
Deposit date:2014-12-28
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4XFT
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STRUCTURE OF IL-18 SER MUTANT III
Descriptor:Interleukin-18, DIMETHYL SULFOXIDE
Authors:Krumm, B.E., Meng, X., Xiang, Y., Deng, J.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4XFU
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STRUCTURE OF IL-18 SER MUTANT V
Descriptor:Interleukin-18
Authors:Krumm, B.E., Meng, X., Xiang, Y., Deng, J.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
5YGI
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CRYSTAL STRUCTURE OF HUMAN FPPS IN COMPLEX WITH AN INHIBITOR THZ93
Descriptor:Farnesyl pyrophosphate synthase, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Li, X.
Deposit date:2017-09-23
Release date:2018-09-26
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.177 Å)
Cite:The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
5GQH
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CRYO-EM STRUCTURE OF PAECAS3-ACRF3 COMPLEX
Descriptor:CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
Authors:Zhang, X., Ma, J., Wang, Y., Wang, J.
Deposit date:2016-08-07
Release date:2016-09-21
Last modified:2016-10-19
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
4W5X
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THE STRUCTURE OF VACCINA VIRUS H7 PROTEIN DISPLAYS A NOVEL PHOSPHOINOSITIDE BINDING FOLD REQUIRED FOR MEMBRANE BIOGENESIS
Descriptor:Late protein H7
Authors:Kolli, S., Deng, J.
Deposit date:2014-08-19
Release date:2014-12-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
4WUM
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X-RAY CRYSTAL STRUCTURE OF CHALCONE SYNTHASE FROM FREESIA HYBRIDA
Descriptor:Chalcone synthase
Authors:Almqvist, J., Jiang, W.S., Wang, L., Huang, Y.
Deposit date:2014-11-02
Release date:2014-11-12
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway.
Plos One, 10, 2015
5GNF
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF3
Descriptor:Uncharacterized protein AcrF3, CALCIUM ION
Authors:Wang, J., Wang, Y.
Deposit date:2016-07-20
Release date:2016-09-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
5IMX
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ANAPLASTIC LYMPHOMA KINASE (ALK) CATALYTIC DOMAIN COMPLEXED WITH NOVEL INHIBITOR 3-SULFONYLPYRAZOL-4-AMINO PYRIMIDINE
Descriptor:ALK tyrosine kinase receptor, 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine
Authors:Wang, C., Zhang, P., Dong, J.
Deposit date:2016-03-07
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5JLJ
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CRYSTAL STRUCTURE OF KPT8602 IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Fung, H.Y., Chook, Y.M.
Deposit date:2016-04-27
Release date:2016-06-29
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Leukemia, 30, 2016
2KOD
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A HIGH-RESOLUTION NMR STRUCTURE OF THE DIMERIC C-TERMINAL DOMAIN OF HIV-1 CA
Descriptor:HIV-1 CA C-terminal domain
Authors:Byeon, I.-J.L., Jung, J., Ahn, J., concel, J., Gronenborn, A.M.
Deposit date:2009-09-18
Release date:2009-11-24
Last modified:2012-03-21
Method:SOLUTION NMR
Cite:Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
Cell(Cambridge,Mass.), 139, 2009
3F62
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CRYSTAL STRUCTURE OF HUMAN IL-18 IN COMPLEX WITH ECTROMELIA VIRUS IL-18 BINDING PROTEIN
Descriptor:Interleukin 18 binding protein, Interleukin-18
Authors:Krumm, B.E., Li, Y., Deng, J.
Deposit date:2008-11-05
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.
Proc.Natl.Acad.Sci.USA, 105, 2008
3J3Q
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ATOMIC-LEVEL STRUCTURE OF THE ENTIRE HIV-1 CAPSID
Descriptor:capsid protein
Authors:Perilla, J.R., Zhao, G., Zhang, P., Schulten, K.J.
Deposit date:2013-04-12
Release date:2013-05-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3J3Y
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ATOMIC-LEVEL STRUCTURE OF THE ENTIRE HIV-1 CAPSID (186 HEXAMERS + 12 PENTAMERS)
Descriptor:capsid protein
Authors:Perilla, J.R., Zhao, G., Zhang, P., Schulten, K.J.
Deposit date:2013-05-06
Release date:2013-05-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3KEA
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STRUCTURE FUNCTION STUDIES OF VACCINIA VIRUS HOST-RANGE PROTEIN K1 REVEAL A NOVEL ANKYRIN REPEAT INTERACTION SURFACE FOR K1S FUNCTION
Descriptor:K1L
Authors:Li, Y.
Deposit date:2009-10-25
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure function studies of vaccinia virus host range protein k1 reveal a novel functional surface for ankyrin repeat proteins.
J.Virol., 84, 2010
4E9O
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VACCINIA D8L ECTODOMAIN STRUCTURE
Descriptor:IMV membrane protein, IODIDE ION
Authors:Matho, M.H., Zajonc, D.M.
Deposit date:2012-03-21
Release date:2012-06-06
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.
J.Virol., 86, 2012
4EBQ
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FAB STRUCTURE OF ANTI-VACCINIA VIRUS D8L ANTIGEN MOUSE IGG2A LA5
Descriptor:anti-Vaccinia D8L antigen monoclonal IgG2a antibody LA5, heavy chain, light chain, ...
Authors:Matho, M.H., Zajonc, D.M.
Deposit date:2012-03-23
Release date:2012-06-06
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.
J.Virol., 86, 2012
4EEE
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CRYSTAL STRUCTURE OF YLDV 14L IL-18 BINDING PROTEIN IN COMPLEX WITH HUMAN IL-18
Descriptor:14L protein, Interleukin-18
Authors:Krumm, B.E., Xiang, Y., Deng, J.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8, 2012
4EKX
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CRYSTAL STRUCTURE OF YLDV 14L IL-18 BINDING PROTEIN IN COMPLEX WITH HUMAN IL-18
Descriptor:14L protein, Interleukin-18
Authors:Krumm, B.E., Xiang, Y., Deng, J.
Deposit date:2012-04-10
Release date:2012-09-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8, 2012
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