9M1H

Cryo-EM structure of PGE2-EP1-Gq complex

Summary for 9M1H

• Entry DOI: 10.2210/pdb9m1h/pdb
• EMDB information: 63571
• Descriptor: Prostaglandin E2 receptor EP1 subtype, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: gpcr, ep1, pge2, gq, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 129700.72

Authors

Meng, X.,Xu, Y.,Xu, H.E. (deposition date: 2025-02-26, release date: 2025-04-30)

• Primary citation: Meng, X.,Xu, Y.,Xu, H.E.; Structural Insights into the Activation of Human Prostaglandin E2 Receptor EP1 Subtype by Prostaglandin E2; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.55 Å)