Author results

1JY9
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MINIMIZED AVERAGE STRUCTURE OF DP-TT2
Descriptor:DP-TT2
Authors:Stanger, H.E., Syud, F.A., Espinosa, J.F., Giriat, I., Muir, T., Gellman, S.H.
Deposit date:2001-09-11
Release date:2001-09-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure.
Proc.Natl.Acad.Sci.USA, 98, 2001
2JM0
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SOLUTION STRUCTURE OF CHICKEN VILLIN HEADPIECE SUBDOMAIN CONTAINING A FLUORINATED SIDE CHAIN IN THE CORE
Descriptor:Villin-1
Authors:Cornilescu, C.C., Cornilescu, G., Hadley, E.B., Gellman, S.H., Markley, J.L.
Deposit date:2006-09-06
Release date:2006-10-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a small protein containing a fluorinated side chain in the core.
Protein Sci., 16, 2007
2N4N
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NMR STRUCTURE FOR A 3-STRANDED PARALLEL BETA-SHEET
Descriptor:DESIGNED BETA SHEET
Authors:Kung, V.M., Cornilescu, G., Gellman, S.H.
Deposit date:2015-06-24
Release date:2015-10-28
Last modified:2016-02-03
Method:SOLUTION NMR
Cite:Impact of Strand Number on Parallel beta-Sheet Stability.
Angew.Chem.Int.Ed.Engl., 54, 2015
2N6H
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NMR STRUCTURE FOR A 2-STRANDED PARALLEL BETA-SHEET
Descriptor:designed 2-stranded parallel beta-sheet
Authors:Kung, V.M., Cornilescu, G., Gellman, S.H.
Deposit date:2015-08-20
Release date:2015-10-28
Last modified:2016-01-27
Method:SOLUTION NMR
Cite:Impact of Strand Number on Parallel beta-Sheet Stability.
Angew.Chem.Int.Ed.Engl., 54, 2015
2N6I
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NMR STRUCTURE FOR A 2-STRANDED PARALLEL BETA-SHEET
Descriptor:designed 2-stranded parallel beta-sheet
Authors:Kung, V.M., Cornilescu, G., Gellman, S.H.
Deposit date:2015-08-20
Release date:2015-10-28
Last modified:2016-01-27
Method:SOLUTION NMR
Cite:Impact of Strand Number on Parallel beta-Sheet Stability.
Angew.Chem.Int.Ed.Engl., 54, 2015
2OXJ
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HELIX BUNDLE QUATERNARY STRUCTURE FROM ALPHA/BETA-PEPTIDE FOLDAMERS: GCN4-P1 WITH BETA-RESIDUES AT B AND F HEPTAD POSITIONS.
Descriptor:hybrid alpha/beta peptide based on the GCN4-p1 sequence; heptad positions b and f substituted with beta-amino acids, ACETATE ION
Authors:Horne, W.S., Price, J.L., Keck, J.L., Gellman, S.H.
Deposit date:2007-02-20
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
2OXK
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HELIX BUNDLE QUATERNARY STRUCTURE FROM ALPHA/BETA-PEPTIDE FOLDAMERS: GCN4-PLI WITH BETA-RESIDUES AT B AND F HEPTAD POSITIONS.
Descriptor:hybrid alpha/beta peptide based on the GCN4-pLI sequence; heptad positions b and f substituted with beta-amino acids, FORMIC ACID
Authors:Horne, W.S., Price, J.L., Keck, J.L., Gellman, S.H.
Deposit date:2007-02-20
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
2YJ1
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PUMA BH3 FOLDAMER IN COMPLEX WITH BCL-XL
Descriptor:BCL-2-LIKE PROTEIN 1, ALPHA-BETA-PUMA BH3 FOLDAMER
Authors:Lee, E.F., Smith, B.J., Horne, W.S., Mayer, K.N., Evangelista, M., Colman, P.M., Gellman, S.H., Fairlie, W.D.
Deposit date:2011-05-18
Release date:2011-10-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural Basis of Bcl-Xl Recognition by a Bh3-Mimetic Alpha-Beta-Peptide Generated Via Sequence-Based Design
Chembiochem, 12, 2011
3C3F
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ALPHA/BETA-PEPTIDE HELIX BUNDLES: THE GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-ALPHA-BETA) BACKBONE
Descriptor:alpha/beta peptide with the GCN4-pLI side chain sequence on an (alpha-alpha-alpha-beta) backbone
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2008-01-28
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C3G
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ALPHA/BETA-PEPTIDE HELIX BUNDLES: THE GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE
Descriptor:alpha/beta peptide with the GCN4-pLI side chain sequence on an (alpha-alpha-beta) backbone, GLYCEROL
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2008-01-28
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C3H
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ALPHA/BETA-PEPTIDE HELIX BUNDLES: A GCN4-PLI ANALOGUE WITH AN (ALPHA-ALPHA-BETA) BACKBONE AND CYCLIC BETA RESIDUES
Descriptor:4, 10, 19, ...
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2008-01-28
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F4Y
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HIV GP41 SIX-HELIX BUNDLE CONTAINING A MUTANT CHR ALPHA-PEPTIDE SEQUENCE
Descriptor:Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain
Authors:Horne, W.S., Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F4Z
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TRIMERIC HELIX BUNDLE FORMED BY AN ALPHA/BETA-PEPTIDE DERIVATIVE OF THE HIV GP41 CHR DOMAIN
Descriptor:alpha/beta-peptide analogue of the HIV gp41 CHR domain, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Horne, W.S., Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F50
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HIV GP41 SIX-HELIX BUNDLE COMPOSED OF AN ALPHA/BETA-PEPTIDE ANALOGUE OF THE CHR DOMAIN IN COMPLEX WITH AN NHR DOMAIN ALPHA-PEPTIDE
Descriptor:Envelope glycoprotein gp160, alpha/beta-peptide analogue of the HIV gp41 CHR domain, GLYCEROL
Authors:Horne, W.S., Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F86
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AN ALPHA/BETA-PEPTIDE HELIX BUNDLE WITH A PURE BETA-AMINO ACID CORE AND A DISTINCTIVE QUATERNARY STRUCTURE: GCN4PLI DERIVATIVE WITH BETA RESIDUES AT A AND D HEPTAD POSITIONS
Descriptor:GCN4pLI-betaAD
Authors:Giuliano, M.W., Horne, W.S., Gellman, S.H.
Deposit date:2008-11-11
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure.
J.Am.Chem.Soc., 131, 2009
3F87
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AN ALPHA/BETA-PEPTIDE HELIX BUNDLE WITH A PURE BETA-AMINO ACID CORE AND A DISTINCTIVE QUARTERNARY STRUCTURE: GCN4PLI DERIVATIVE WITH BETA RESIDUES AT A AND D HEPTAD POSITIONS - HIGHER SYMMETRY CRYSTAL
Descriptor:GCN4pLI-betaAD, IODIDE ION
Authors:Giuliano, M.W., Horne, W.S., Gellman, S.H.
Deposit date:2008-11-11
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure.
J.Am.Chem.Soc., 131, 2009
3FDM
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ALPHA/BETA FOLDAMER IN COMPLEX WITH BCL-XL
Descriptor:Apoptosis regulator Bcl-X, alpha/beta-peptide foldamer, 1,2-ETHANEDIOL
Authors:Fairlie, W.D., Lee, E.F., Smith, B.J., Czabotar, P.E., Colman, P.M., Sadowsky, J.D., Peterson-Kaufman, K.J., Gellman, S.H.
Deposit date:2008-11-26
Release date:2009-03-10
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)
Angew.Chem.Int.Ed.Engl., 48, 2009
3G7A
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HIV GP41 SIX-HELIX BUNDLE COMPOSED OF A CHIMERIC ALPHA+ALPHA/BETA-PEPTIDE ANALOGUE OF THE CHR DOMAIN IN COMPLEX WITH AN NHR DOMAIN ALPHA-PEPTIDE
Descriptor:Envelope glycoprotein gp160, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, ACETYL GROUP, ...
Authors:Horne, W.S., Johnson, L.M., Gellman, S.H.
Deposit date:2009-02-09
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3HET
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH A CYCLIC BETA-RESIDUE AT POSITION 10
Descriptor:alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and a cyclic beta-residue at position 10
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEU
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH A CYCLIC BETA-RESIDUE AT POSITION 13
Descriptor:alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and a cyclic beta-residue at position 13, NONAETHYLENE GLYCOL
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEV
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH A CYCLIC BETA-RESIDUE AT POSITION 19
Descriptor:alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and a cyclic beta-residue at position 19
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEW
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH A CYCLIC BETA-RESIDUE AT POSITION 22
Descriptor:alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and a cyclic beta-residue at position 22
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEX
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH CYCLIC BETA-RESIDUES AT POSITIONS 1, 4, 19 AND 28
Descriptor:4, alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and cyclic beta-residues at positions 1, 19 and 28
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEY
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CYCLIC RESIDUES IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: GCN4-PLI SIDE CHAIN SEQUENCE ON AN (ALPHA-ALPHA-BETA) BACKBONE WITH CYCLIC BETA-RESIDUES AT POSITIONS 1, 4, 10, 19 AND 28
Descriptor:4, 10, alpha/beta-peptide based on the GCN4-pLI side chain sequence with an (alpha-alpha-beta) backbone and cyclic beta-residues at positions 1, ...
Authors:Horne, W.S., Price, J.L., Gellman, S.H.
Deposit date:2009-05-10
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
J.Am.Chem.Soc., 132, 2010
3HEZ
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EXPLORING BACKBONE PATTERN IN ALPHA/BETA-PEPTIDE HELIX BUNDLES: THE GCN4-PLI SIDE CHAIN SEQUENCE ON DIFFERENT (ALPHA-ALPHA-ALPHA-BETA) BACKBONES
Descriptor:alpha/beta peptide with the GCN4-pLI side chain sequence on an (alpha-alpha-alpha-beta) backbone, TERTIARY-BUTYL ALCOHOL, GLYCEROL, ...
Authors:Horne, W.S., Gellman, S.H.
Deposit date:2009-05-10
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploring backbone pattern in GCN4-pLI alpha/beta-peptide helix bundles
To be Published
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