4A1U
Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL
Summary for 4A1U
Entry DOI | 10.2210/pdb4a1u/pdb |
Related | 1BXL 1G5J 1LXL 1MAZ 1R2D 1R2E 1R2G 1R2H 1R2I 1YSG 1YSI 1YSN 2B48 2YJ1 4A1W |
Descriptor | BCL-2-LIKE PROTEIN 1, ALPHA-BETA-FOLDAMER 2C, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | apoptosis, alpha-helix, bh3, mimicry |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 20437.62 |
Authors | Boersma, M.D.,Haase, H.S.,Kaufman, K.J.,Horne, W.S.,Lee, E.F.,Clarke, O.B.,Smith, B.J.,Colman, P.M.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2011-09-20, release date: 2011-12-28, Last modification date: 2023-12-20) |
Primary citation | Boersma, M.D.,Haase, H.S.,Peterson-Kaufman, K.J.,Lee, E.F.,Clarke, O.B.,Colman, P.M.,Smith, B.J.,Horne, W.S.,Fairlie, W.D.,Gellman, S.H. Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain. J.Am.Chem.Soc., 134:315-, 2012 Cited by PubMed: 22040025DOI: 10.1021/JA207148M PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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