4A1U
Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BCL-2-LIKE PROTEIN 1 | polymer | 158 | 17918.0 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | HOMO SAPIENS (HUMAN) | BCL-XL, BCL2-L-1, APOPTOSIS REGULATOR BCL-X |
| 2 | B (B) | ALPHA-BETA-FOLDAMER 2C | polymer | 20 | 2352.7 | 1 | Pfam (PF08945) UniProt (by SIFTS) (O43521) | SYNTHETIC CONSTRUCT | |
| 3 | C, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 1 - 26 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20270.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 167.0 | |
| All* | Total formula weight | 20437.6 |
