8D51

Parathyroid hormone 1 receptor extracellular domain complexed with a peptide ligand containing beta-3-homotryptophan

Summary for 8D51

Entry DOI	10.2210/pdb8d51/pdb
Descriptor	Parathyroid hormone/parathyroid hormone-related peptide receptor, PTHrP[1-36], 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	parathyroid hormone 1 receptor, signaling, beta-amino acid, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	14945.42
Authors	Yu, Z.,Kreitler, D.F.,Gellman, S.H. (deposition date: 2022-06-03, release date: 2023-06-14, Last modification date: 2023-12-27)
Primary citation	Yu, Z.,Kreitler, D.F.,Chiu, Y.T.T.,Xu, R.,Bruchs, A.T.,Bingman, C.A.,Gellman, S.H. Harnessing Aromatic-Histidine Interactions through Synergistic Backbone Extension and Side Chain Modification. Angew.Chem.Int.Ed.Engl., 62:e202308100-e202308100, 2023 Cited by PubMed: 37587780 DOI: 10.1002/anie.202308100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation