4BPJ

Mcl-1 bound to alpha beta Puma BH3 peptide 3

Summary for 4BPJ

• Entry DOI: 10.2210/pdb4bpj/pdb
• Related: 4BPI 4BPK
• Descriptor: FUSION PROTEIN CONSISTING OF INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 HOMOLOG, ALPHA BETA BH3-PEPTIDE, ZINC ION, ... (5 entities in total)
• Functional Keywords: apoptosis, chimera, bim
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 2
• Total formula weight: 20800.84

Authors

Smith, B.J.,Lee, E.F.,Checco, J.W.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2013-05-27, release date: 2014-04-09, Last modification date: 2024-05-15)

• Primary citation: Smith, B.J.,Lee, E.F.,Checco, J.W.,Evangelista, M.,Gellman, S.H.,Fairlie, W.D.; Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.; Chembiochem, 14:1564-, 2013; PubMed: 23929624; DOI: 10.1002/CBIC.201300351

Experimental method

X-RAY DIFFRACTION (1.599 Å)