2YJ1
Puma BH3 foldamer in complex with Bcl-xL
Summary for 2YJ1
Entry DOI | 10.2210/pdb2yj1/pdb |
Related | 1BXL 1G5J 1LXL 1MAZ 1R2D 1R2E 1R2G 1R2H 1R2I 1YSG 1YSI 1YSN 2B48 |
Descriptor | BCL-2-LIKE PROTEIN 1, ALPHA-BETA-PUMA BH3 FOLDAMER (3 entities in total) |
Functional Keywords | apoptosis, membrane protein, foldamer, bh3 domain, autophagy |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 41069.87 |
Authors | Lee, E.F.,Smith, B.J.,Horne, W.S.,Mayer, K.N.,Evangelista, M.,Colman, P.M.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2011-05-18, release date: 2011-10-12, Last modification date: 2023-12-20) |
Primary citation | Lee, E.F.,Smith, B.J.,Horne, W.S.,Mayer, K.N.,Evangelista, M.,Colman, P.M.,Gellman, S.H.,Fairlie, W.D. Structural Basis of Bcl-Xl Recognition by a Bh3-Mimetic Alpha-Beta-Peptide Generated Via Sequence-Based Design Chembiochem, 12:2025-, 2011 Cited by PubMed: 21744457DOI: 10.1002/CBIC.201100314 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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