2YJ1
Puma BH3 foldamer in complex with Bcl-xL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | BCL-2-LIKE PROTEIN 1 | polymer | 158 | 17918.0 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | HOMO SAPIENS (HUMAN) | BCL2-L-1, APOPTOSIS REGULATOR BCL-X BCL-XL |
| 2 | B, D (B, D) | ALPHA-BETA-PUMA BH3 FOLDAMER | polymer | 23 | 2617.0 | 2 | SYNTHETIC CONSTRUCT | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 26 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | cloning artifact |
| Pro -3 | - | cloning artifact |
| Leu -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41069.9 | |
| All* | Total formula weight | 41069.9 |
