4BPK

Bcl-xL bound to alpha beta Puma BH3 peptide 5

Summary for 4BPK

• Entry DOI: 10.2210/pdb4bpk/pdb
• Related: 4BPI 4BPJ
• Descriptor: BCL-2-LIKE PROTEIN 1, ALPHA BETA BH3-PEPTIDE, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: apoptosis
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 42475.84

Authors

Smith, B.J.,Lee, E.F.,Checco, J.W.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2013-05-27, release date: 2014-04-09, Last modification date: 2023-12-20)

• Primary citation: Smith, B.J.,Lee, E.F.,Checco, J.W.,Evangelista, M.,Gellman, S.H.,Fairlie, W.D.; Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.; Chembiochem, 14:1564-, 2013; PubMed: 23929624; DOI: 10.1002/CBIC.201300351

Experimental method

X-RAY DIFFRACTION (1.756 Å)