Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0043065 | biological_process | positive regulation of apoptotic process |
| C | 0090200 | biological_process | positive regulation of release of cytochrome c from mitochondria |
| C | 0097193 | biological_process | intrinsic apoptotic signaling pathway |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0043065 | biological_process | positive regulation of apoptotic process |
| D | 0090200 | biological_process | positive regulation of release of cytochrome c from mitochondria |
| D | 0097193 | biological_process | intrinsic apoptotic signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1196 |
| Chain | Residue |
| B | GLY186 |
| B | ASP189 |
| B | HOH2069 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1197 |
| Chain | Residue |
| A | GLY186 |
| A | ASP189 |
| B | ASP176 |
| B | HOH2058 |
| B | HOH2073 |
| B | HOH2074 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 1198 |
| Chain | Residue |
| B | HIS177 |
| B | HOH2059 |
| B | HOH2060 |
| B | HOH2063 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1196 |
| Chain | Residue |
| A | GLU129 |
| A | GLU158 |
| A | HOH2059 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1197 |
| Chain | Residue |
| A | GLU92 |
| A | HOH2023 |
| A | HOH2042 |
| A | HOH2043 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD A 1198 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1199 |
| Chain | Residue |
| A | GLU153 |
| A | HOH2051 |
| A | HOH2064 |
| A | HOH2065 |
| A | HOH2066 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1199 |
| Chain | Residue |
| B | GLN88 |
| B | GLU92 |
| B | HOH2012 |
| B | HOH2026 |
| B | HOH2075 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1200 |
| Chain | Residue |
| B | GLU129 |
| D | ARG3 |
| D | B3E4 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1201 |
| Chain | Residue |
| B | ASP156 |
| B | HOH2052 |
| B | HOH2053 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD A 1200 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 1202 |
| Chain | Residue |
| B | HIS113 |
| C | B3D15 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 1203 |
| Chain | Residue |
| B | HIS113 |
| C | B3D15 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 1204 |
| Chain | Residue |
| B | GLU158 |
| B | HOH2076 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1201 |
| Chain | Residue |
| A | GLU179 |
| A | HOH2068 |
| A | HOH2069 |
| B | GLU124 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1205 |
| Chain | Residue |
| B | ASN136 |
| B | HOH2047 |
| B | HOH2077 |
| B | HOH2078 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1202 |
| Chain | Residue |
| A | GLN88 |
| A | ARG91 |
| B | ASP11 |
| B | ARG91 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
