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5L2R
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CRYSTAL STRUCTURE OF FUMARATE HYDRATASE FROM LEISHMANIA MAJOR
Descriptor:Fumarate hydratase, (2S)-2-hydroxybutanedioic acid, MALONIC ACID, ...
Authors:Feliciano, P.R., Drennan, C.L., Nonato, M.C.
Deposit date:2016-08-02
Release date:2016-08-17
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from Leishmania major reveals a unique protein fold.
Proc.Natl.Acad.Sci.USA, 113, 2016
5TS5
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CRYSTAL STRUCTURE OF L-AMINO ACID OXIDASE FROM BOTHROPS ATROX
Descriptor:Amine oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ...
Authors:Feliciano, P.R., Nonato, M.C.
Deposit date:2016-10-27
Release date:2017-04-26
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and molecular dynamics studies of L-amino acid oxidase from Bothrops atrox.
Toxicon, 128, 2017
6MSN
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH INHIBITOR THIOMALATE
Descriptor:fumarate hydratase, IRON/SULFUR CLUSTER, (2S)-2-sulfanylbutanedioic acid
Authors:Feliciano, P.R., Drennan, C.L., Nonato, M.C.
Deposit date:2018-10-17
Release date:2019-01-30
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.591 Å)
Cite:Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6MSO
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CRYSTAL STRUCTURE OF MITOCHONDRIAL FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH INHIBITOR THIOMALATE
Descriptor:fumarate hydratase, IRON/SULFUR CLUSTER, GLYCEROL, ...
Authors:Feliciano, P.R., Drennan, C.L., Nonato, M.C.
Deposit date:2018-10-17
Release date:2019-01-30
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6UNZ
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR
Descriptor:fumarate hydratase 2, IRON/SULFUR CLUSTER, GLYCEROL
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-14
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UO0
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-14
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UOI
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH MALONATE
Descriptor:Fumarate hydratase 2, MALONIC ACID, GLYCEROL, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UOJ
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH SUCCINATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, SUCCINIC ACID, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UP9
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CRYSTAL STRUCTURE OF T467A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH MALONATE
Descriptor:Fumarate hydratase 2, MALONIC ACID, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-16
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UPM
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CRYSTAL STRUCTURE OF T467A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-17
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UPO
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CRYSTAL STRUCTURE OF H334A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.113 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQ8
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CRYSTAL STRUCTURE OF R421A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE AND MALONATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.339 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQ9
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CRYSTAL STRUCTURE OF R421A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, (2S)-2-hydroxybutanedioic acid, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQB
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CRYSTAL STRUCTURE OF R471A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE AND MALONATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQL
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CRYSTAL STRUCTURE OF R471A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQM
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CRYSTAL STRUCTURE OF R173A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQN
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CRYSTAL STRUCTURE OF R173A VARIANT OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH FUMARATE AND S-MALATE
Descriptor:Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ...
Authors:Feliciano, P.R., Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
3GYE
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DIDYDROOROTATE DEHYDROGENASE FROM LEISHMANIA MAJOR
Descriptor:Dihydroorotate dehydrogenase, putative, FLAVIN MONONUCLEOTIDE, ...
Authors:Cordeiro, A.T., Feliciano, P.R., Nonato, M.C.
Deposit date:2009-04-03
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Leishmania major Dihydroorotate dehydrogenase
To be Published
3GZ3
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LEISHMANIA MAJOR DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH OROTATE
Descriptor:Dihydroorotate dehydrogenase, putative, FLAVIN MONONUCLEOTIDE, ...
Authors:Cordeiro, A.T., Feliciano, P.R., Nonato, M.C.
Deposit date:2009-04-06
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Leismania major dihydroorotate in complex with orotate
To be Published
3TQ0
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH FUMARATE
Descriptor:Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, FUMARIC ACID, ...
Authors:Cordeiro, A.T., Feliciano, P.R., Nonato, M.C.
Deposit date:2011-09-08
Release date:2012-05-16
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of dihydroorotate dehydrogenase from Leishmania major.
Biochimie, 94, 2012
6DTD
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF CAS13B FROM PREVOTELLA BUCCAE
Descriptor:nuclease, RNA (37-MER), CITRIC ACID, ...
Authors:Slaymaker, I.M.S., Zhang, F.Z.
Deposit date:2018-06-15
Release date:2019-02-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.
Cell Rep, 26, 2019
Protein Data Bank Japan - PDBj
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