6UP9
Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Summary for 6UP9
Entry DOI | 10.2210/pdb6up9/pdb |
Related | 6UNZ 6UO0 6UOI 6UOJ |
Descriptor | Fumarate hydratase 2, MALONIC ACID, IRON/SULFUR CLUSTER, ... (5 entities in total) |
Functional Keywords | fumarate hydratase, fumarase, leishmania major, inhibitor, variant t467a, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Leishmania major strain Friedlin |
Total number of polymer chains | 2 |
Total formula weight | 134386.63 |
Authors | Feliciano, P.R.,Drennan, C.L. (deposition date: 2019-10-16, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Feliciano, P.R.,Drennan, C.L. Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major. Biochemistry, 58:5011-5021, 2019 Cited by PubMed: 31743022DOI: 10.1021/acs.biochem.9b00923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.949 Å) |
Structure validation
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