6UOI
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Summary for 6UOI
| Entry DOI | 10.2210/pdb6uoi/pdb |
| Related | 6UNZ 6UO0 6UOJ |
| Descriptor | Fumarate hydratase 2, MALONIC ACID, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | fumarate hydratase, fumarase, leishmania major, inhibitor, malonate, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Leishmania major strain Friedlin |
| Total number of polymer chains | 2 |
| Total formula weight | 134446.68 |
| Authors | Feliciano, P.R.,Drennan, C.L. (deposition date: 2019-10-15, release date: 2019-12-04, Last modification date: 2023-10-11) |
| Primary citation | Feliciano, P.R.,Drennan, C.L. Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major. Biochemistry, 58:5011-5021, 2019 Cited by PubMed: 31743022DOI: 10.1021/acs.biochem.9b00923 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.953 Å) |
Structure validation
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