Crystal structure of fumarate hydratase from Leishmania major

Replaces:  4LOZ

Summary for 5L2R

DescriptorFumarate hydratase, (2S)-2-hydroxybutanedioic acid, MALONIC ACID, ... (7 entities in total)
Functional Keywordsfumarate hydratase fe-s cluster, lyase
Biological sourceLeishmania major
Total number of polymer chains2
Total molecular weight135525.68
Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. (deposition date: 2016-08-02, release date: 2016-08-17, Last modification date: 2017-09-20)
Primary citation
Feliciano, P.R.,Drennan, C.L.,Nonato, M.C.
Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from Leishmania major reveals a unique protein fold.
Proc.Natl.Acad.Sci.USA, 113:9804-9809, 2016
PubMed: 27528683 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1605031113
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.177201.6%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5l2r
no rotation
Molmil generated image of 5l2r
rotated about x axis by 90°
Molmil generated image of 5l2r
rotated about y axis by 90°
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