6UOJ

Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with succinate

Summary for 6UOJ

Entry DOI	10.2210/pdb6uoj/pdb
Related	6UNZ 6UO0 6UOI
Descriptor	Fumarate hydratase 2, IRON/SULFUR CLUSTER, SUCCINIC ACID, ... (5 entities in total)
Functional Keywords	fumarate hydratase, fumarase, leishmania major, inhibitor, succinate, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Leishmania major strain Friedlin
Total number of polymer chains	2
Total formula weight	134150.58
Authors	Feliciano, P.R.,Drennan, C.L. (deposition date: 2019-10-15, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citation	Feliciano, P.R.,Drennan, C.L. Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major. Biochemistry, 58:5011-5021, 2019 Cited by PubMed: 31743022 DOI: 10.1021/acs.biochem.9b00923 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation