8E2R

Crystal structure of TadAC-1.14

Summary for 8E2R

Entry DOI	10.2210/pdb8e2r/pdb
Descriptor	tRNA-specific adenosine deaminase 1.14, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	deaminase, tadac, dna binding protein
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	37894.60
Authors	Feliciano, P.R.,Lee, S.J.,Ciaramella, G. (deposition date: 2022-08-15, release date: 2023-01-11, Last modification date: 2023-10-25)
Primary citation	Lam, D.K.,Feliciano, P.R.,Arif, A.,Bohnuud, T.,Fernandez, T.P.,Gehrke, J.M.,Grayson, P.,Lee, K.D.,Ortega, M.A.,Sawyer, C.,Schwaegerle, N.D.,Peraro, L.,Young, L.,Lee, S.J.,Ciaramella, G.,Gaudelli, N.M. Improved cytosine base editors generated from TadA variants. Nat.Biotechnol., 41:686-697, 2023 Cited by PubMed: 36624149 DOI: 10.1038/s41587-022-01611-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation