8E2P

Crystal structure of TadA*8.20 in a complex with ssDNA

Summary for 8E2P

• Entry DOI: 10.2210/pdb8e2p/pdb
• Descriptor: tRNA-specific adenosine deaminase 8.20, DNA (5'-D(P*GP*CP*TP*CP*GP*GP*CP*TP*(D8A)P*CP*GP*GP*A)-3'), ZINC ION, ... (4 entities in total)
• Functional Keywords: deaminase, ssdna, tada, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 8
• Total formula weight: 91198.67

Authors

Feliciano, P.R.,Lee, S.J.,Ciaramella, G. (deposition date: 2022-08-15, release date: 2023-01-11, Last modification date: 2023-10-25)

• Primary citation: Lam, D.K.,Feliciano, P.R.,Arif, A.,Bohnuud, T.,Fernandez, T.P.,Gehrke, J.M.,Grayson, P.,Lee, K.D.,Ortega, M.A.,Sawyer, C.,Schwaegerle, N.D.,Peraro, L.,Young, L.,Lee, S.J.,Ciaramella, G.,Gaudelli, N.M.; Improved cytosine base editors generated from TadA variants.; Nat.Biotechnol., 41:686-697, 2023; PubMed: 36624149; DOI: 10.1038/s41587-022-01611-9

Experimental method

X-RAY DIFFRACTION (2.72 Å)