8E2P
Crystal structure of TadA*8.20 in a complex with ssDNA
Summary for 8E2P
Entry DOI | 10.2210/pdb8e2p/pdb |
Descriptor | tRNA-specific adenosine deaminase 8.20, DNA (5'-D(P*GP*CP*TP*CP*GP*GP*CP*TP*(D8A)P*CP*GP*GP*A)-3'), ZINC ION, ... (4 entities in total) |
Functional Keywords | deaminase, ssdna, tada, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Escherichia coli More |
Total number of polymer chains | 8 |
Total formula weight | 91198.67 |
Authors | Feliciano, P.R.,Lee, S.J.,Ciaramella, G. (deposition date: 2022-08-15, release date: 2023-01-11, Last modification date: 2023-10-25) |
Primary citation | Lam, D.K.,Feliciano, P.R.,Arif, A.,Bohnuud, T.,Fernandez, T.P.,Gehrke, J.M.,Grayson, P.,Lee, K.D.,Ortega, M.A.,Sawyer, C.,Schwaegerle, N.D.,Peraro, L.,Young, L.,Lee, S.J.,Ciaramella, G.,Gaudelli, N.M. Improved cytosine base editors generated from TadA variants. Nat.Biotechnol., 41:686-697, 2023 Cited by PubMed: 36624149DOI: 10.1038/s41587-022-01611-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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