9AV9

R2-state HbG-Makassar hemoglobin

Summary for 9AV9

• Entry DOI: 10.2210/pdb9av9/pdb
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, GLYCEROL, ... (5 entities in total)
• Functional Keywords: hemoglobin, makassar, sickle, e6a, oxygen transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 64891.45

Authors

Feliciano, P.R.,Lee, S.J. (deposition date: 2024-03-01, release date: 2024-12-11)

• Primary citation: Kostamo, Z.,Ortega, M.A.; Installation of HbG- Makassar by base editing restores hemoglobin function: a transformative therapy for sickle cell disease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)