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2AM9
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CRYSTAL STRUCTURE OF HUMAN ANDROGEN RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH TESTOSTERONE
Descriptor:Androgen receptor, SULFATE ION, TESTOSTERONE, ...
Authors:Pereira de Jesus-Tran, K., Cote, P.-L., Cantin, L., Blanchet, J., Labrie, F., Breton, R.
Deposit date:2005-08-09
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.
Protein Sci., 15, 2006
2AMA
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CRYSTAL STRUCTURE OF HUMAN ANDROGEN RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor:Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Pereira de Jesus-Tran, K., Cote, P.-L., Cantin, L., Blanchet, J., Labrie, F., Breton, R.
Deposit date:2005-08-09
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.
Protein Sci., 15, 2006
2AMB
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CRYSTAL STRUCTURE OF HUMAN ANDROGEN RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH TETRAHYDROGESTRINONE
Descriptor:Androgen receptor, SULFATE ION, 17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE, ...
Authors:Pereira de Jesus-Tran, K., Cote, P.-L., Cantin, L., Blanchet, J., Labrie, F., Breton, R.
Deposit date:2005-08-09
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.
Protein Sci., 15, 2006
3EIG
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CRYSTAL STRUCTURE OF A METHOTREXATE-RESISTANT MUTANT OF HUMAN DIHYDROFOLATE REDUCTASE
Descriptor:Dihydrofolate reductase, METHOTREXATE, SULFATE ION, ...
Authors:Yachnin, B.J., Berghuis, A.M.
Deposit date:2008-09-15
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.
J.Biol.Chem., 284, 2009
5IGH
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I
Descriptor:Macrolide 2'-phosphotransferase, SULFATE ION
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGI
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOSINE AND AZITHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase, GUANOSINE, AZITHROMYCIN, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGJ
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOSINE AND CLARITHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase, GUANOSINE, CLARITHROMYCIN, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGP
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GDP AND ERYTHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase, GUANOSINE-5'-DIPHOSPHATE, ERYTHROMYCIN A, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGR
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GDP AND OLEANDOMYCIN
Descriptor:Macrolide 2'-phosphotransferase, GUANOSINE-5'-DIPHOSPHATE, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGS
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOSINE AND OLEANDOMYCIN
Descriptor:Macrolide 2'-phosphotransferase, ISOPROPYL ALCOHOL, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGT
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOSINE AND ERYTHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase, GUANOSINE, ERYTHROMYCIN A, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGU
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II
Descriptor:Macrolide 2'-phosphotransferase II
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGV
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND AZITHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, MAGNESIUM ION, CALCIUM ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGW
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND CLARITHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGY
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND ERYTHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IGZ
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND SPIRAMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IH0
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II Y92M MUTANT - COMPLEX WITH GDP AND ERYTHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, MAGNESIUM ION, ACETATE ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IH1
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND PHOSPHORYLATED JOSAMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-02-28
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
5IWU
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MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II COMPLEXED WITH ERYTHROMYCIN
Descriptor:Macrolide 2'-phosphotransferase II, GLYCEROL, ACETATE ION, ...
Authors:Berghuis, A.M., Fong, D.H.
Deposit date:2016-03-22
Release date:2017-04-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017