5IH1
Macrolide 2'-phosphotransferase type II - complex with GDP and phosphorylated josamycin
Summary for 5IH1
| Entry DOI | 10.2210/pdb5ih1/pdb |
| Related | 5IGU 5IGV 5IGW 5IGY 5IGZ 5IH0 |
| Descriptor | Macrolide 2'-phosphotransferase II, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | macrolide phosphotransferase, kinase, transferase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 35946.80 |
| Authors | Berghuis, A.M.,Fong, D.H. (deposition date: 2016-02-28, release date: 2017-04-26, Last modification date: 2024-03-06) |
| Primary citation | Fong, D.H.,Burk, D.L.,Blanchet, J.,Yan, A.Y.,Berghuis, A.M. Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25:750-761.e5, 2017 Cited by PubMed: 28416110DOI: 10.1016/j.str.2017.03.007 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.31 Å) |
Structure validation
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