5IGJ

Macrolide 2'-phosphotransferase type I - complex with guanosine and clarithromycin

Summary for 5IGJ

Entry DOI	10.2210/pdb5igj/pdb
Related	5IGH 5IGI 5IGP 5IGR 5IGS 5IGT 5IGU 5IGV 5IGW 5IGY 5IGZ 5IH0 5IH1
Descriptor	Macrolide 2'-phosphotransferase, GUANOSINE, CLARITHROMYCIN, ... (5 entities in total)
Functional Keywords	macrolide phosphotransferase, kinase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	34358.12
Authors	Berghuis, A.M.,Fong, D.H. (deposition date: 2016-02-28, release date: 2017-04-26, Last modification date: 2023-09-27)
Primary citation	Fong, D.H.,Burk, D.L.,Blanchet, J.,Yan, A.Y.,Berghuis, A.M. Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25:750-761.e5, 2017 Cited by PubMed: 28416110 DOI: 10.1016/j.str.2017.03.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation