2AMA
Crystal structure of human androgen receptor ligand binding domain in complex with dihydrotestosterone
Summary for 2AMA
Entry DOI | 10.2210/pdb2ama/pdb |
Related | 2AM9 2AMB |
Descriptor | Androgen receptor, SULFATE ION, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total) |
Functional Keywords | nuclear receptor, androgen receptor, ligand binding domain, dht, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P10275 |
Total number of polymer chains | 1 |
Total formula weight | 31382.69 |
Authors | Pereira de Jesus-Tran, K.,Cote, P.-L.,Cantin, L.,Blanchet, J.,Labrie, F.,Breton, R. (deposition date: 2005-08-09, release date: 2006-05-16, Last modification date: 2023-08-23) |
Primary citation | Pereira de Jesus-Tran, K.,Cote, P.-L.,Cantin, L.,Blanchet, J.,Labrie, F.,Breton, R. Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity. Protein Sci., 15:987-999, 2006 Cited by PubMed: 16641486DOI: 10.1110/ps.051905906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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