7MQK

AAC(3)-IIIa in complex with CoA and sisomicin

Summary for 7MQK

Entry DOI	10.2210/pdb7mqk/pdb
Descriptor	Aminoglycoside N(3)-acetyltransferase III, (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, COENZYME A, ... (5 entities in total)
Functional Keywords	antibiotic resistance, aminoglycoside, acetyltransferase, transferase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	124744.11
Authors	Zielinski, M.,Berghuis, A.M. (deposition date: 2021-05-05, release date: 2022-07-06, Last modification date: 2023-11-15)
Primary citation	Zielinski, M.,Blanchet, J.,Hailemariam, S.,Berghuis, A.M. Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One, 17:e0269684-e0269684, 2022 Cited by PubMed: 35921328 DOI: 10.1371/journal.pone.0269684 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation