1HUU | |
6DB0 | |
6DBC | | SECOND BROMODOMAIN OF HUMAN BRD2 WITH A TETRAHYDROQUINOLINE ANALOGUE | | Descriptor: | Bromodomain-containing protein 2, 1,2-ETHANEDIOL, 1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2018-05-03 | | Release date: | 2019-11-13 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue
To Be Published
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6DDI | | CRYSTAL STRUCTURE OF THE HUMAN BRD2 BD1 BROMODOMAIN IN COMPLEX WITH A TETRAHYDROQUINOLINE ANALOGUE | | Descriptor: | Bromodomain-containing protein 2, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, SULFATE ION, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2018-05-10 | | Release date: | 2019-11-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue
To Be Published
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6DDJ | | CRYSTAL STRUCTURE OF THE HUMAN BRD2 BD2 BROMODIMAIN IN COMPLEX WITH A TETRAHYDROQUINOLINE ANALOGUE | | Descriptor: | Bromodomain-containing protein 2, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, 1,2-ETHANEDIOL | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2018-05-10 | | Release date: | 2019-11-13 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Crystal Structure of the human BRD2 BD2 bromodimain in complex with a Tetrahydroquinoline analogue
To Be Published
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3TYA | |
5KPR | | PANK3-AMPPNP-PANTOTHENATE COMPLEX | | Descriptor: | Pantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2016-07-05 | | Release date: | 2016-08-31 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (1.827 Å) | | Cite: | Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
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5KPT | | PANK3-AMPPNP COMPLEX | | Descriptor: | Pantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2016-07-05 | | Release date: | 2016-08-31 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
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5KPZ | | PANK3-ADP-PHOSPHOPANTOTHENATE COMPLEX | | Descriptor: | Pantothenate kinase 3, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2016-07-05 | | Release date: | 2016-08-31 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
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5KQ8 | | PANK3-AMPPN COMPLEX | | Descriptor: | Pantothenate kinase 3, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2016-07-05 | | Release date: | 2016-08-31 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
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5KQD | | PANK3:PALMITOYL-COA COMPLEX | | Descriptor: | Pantothenate kinase 3, Palmitoyl-CoA, SULFATE ION | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2016-07-06 | | Release date: | 2016-08-31 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
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6ATH | | CDK2/CYCLIN A/P27-KID-DELTAC | | Descriptor: | Cyclin-dependent kinase 2, Cyclin-A2, Cyclin-dependent kinase inhibitor 1B, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2017-08-29 | | Release date: | 2018-09-12 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.
Nat Commun, 10, 2019
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6B3V | | PANK3 COMPLEX WITH COMPOUND PZ-2891 | | Descriptor: | Pantothenate kinase 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... | | Authors: | White, S.W., Yun, M. | | Deposit date: | 2017-09-25 | | Release date: | 2018-08-29 | | Last modified: | 2018-11-28 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | A therapeutic approach to pantothenate kinase associated neurodegeneration.
Nat Commun, 9, 2018
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1PKP | |
1DIV | | RIBOSOMAL PROTEIN L9 | | Descriptor: | RIBOSOMAL PROTEIN L9 | | Authors: | Hoffman, D.W., Cameron, C., Davies, C., Gerchman, S.E., Kycia, J.H., Porter, S., Ramakrishnan, V., White, S.W. | | Deposit date: | 1996-07-02 | | Release date: | 1997-01-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
EMBO J., 13, 1994
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1RL6 | | RIBOSOMAL PROTEIN L6 | | Descriptor: | PROTEIN (RIBOSOMAL PROTEIN L6) | | Authors: | Golden, B.L., Davies, C., Ramakrishnan, V., White, S.W. | | Deposit date: | 1999-01-14 | | Release date: | 1999-02-02 | | Last modified: | 2019-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
EMBO J., 12, 1993
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1WHI | | RIBOSOMAL PROTEIN L14 | | Descriptor: | RIBOSOMAL PROTEIN L14 | | Authors: | Davies, C., White, S.W., Ramakrishnan, V. | | Deposit date: | 1996-01-10 | | Release date: | 1996-08-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus.
Structure, 4, 1996
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5CCY | | 2009 H1N1 PA ENDONUCLEASE IN COMPLEX WITH DTMP | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, THYMIDINE-5'-PHOSPHATE | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-07-02 | | Release date: | 2016-03-16 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5CGV | | 2009 H1N1 PA ENDONUCLEASE IN COMPLEX WITH L-742,001 | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, ... | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-07-09 | | Release date: | 2016-03-23 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5CL0 | | 2009 H1N1 PA ENDONUCLEASE IN COMPLEX WITH RUMP | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-07-15 | | Release date: | 2016-03-16 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5CZN | | 2009 H1N1 PA ENDONUCLEASE MUTANT E119D | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, SULFATE ION | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-07-31 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5D2O | | 2009 H1N1 PA ENDONUCLEASE MUTANT F105S | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-08-05 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5D42 | | 2009 H1N1 PA ENDONUCLEASE MUTANT F105S IN COMPLEX WITH DTMP | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, THYMIDINE-5'-PHOSPHATE | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-08-07 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5D4G | | 2009 H1N1 PA ENDONUCLEASE MUTANT F105S IN COMPLEX WITH RUMP | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-08-07 | | Release date: | 2016-03-23 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5D8U | | 2009 H1N1 PA ENDONUCLEASE MUTANT E119D IN COMPLEX WITH L-742,001 | | Descriptor: | Polymerase acidic protein, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid | | Authors: | Kumar, G., White, S.W. | | Deposit date: | 2015-08-18 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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