7UES
PANK3 complex structure with compound PZ-4202
Summary for 7UES
Entry DOI | 10.2210/pdb7ues/pdb |
Descriptor | Pantothenate kinase 3, N-(4-{2-[4-(6-cyanopyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)methanesulfonamide, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pank, transferase, inhibitor, activator, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 43056.71 |
Authors | White, S.W.,Yun, M.,Lee, R.E. (deposition date: 2022-03-22, release date: 2023-03-29, Last modification date: 2023-10-25) |
Primary citation | Tangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E. Discovery of hPANK Activators with Improved Pharmacological Properties To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report